相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。An Unbiased Approach To Identify Endogenous Substrates of Histone Deacetylase 8
David E. Olson et al.
ACS CHEMICAL BIOLOGY (2014)
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling
Kimberly M. Demos-Davies et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
Novel and Emerging Therapies for Pulmonary Hypertension
Soni Savai Pullamsetti et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration
Margherita Galletti et al.
BIOCHEMICAL PHARMACOLOGY (2014)
MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts
Daren Wang et al.
CIRCULATION RESEARCH (2014)
BET-ting on chromatin-based therapeutics for heart failure
Saptarsi M. Haldar et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Epigenetic regulation of fibrocyte differentiation?
Marta Lishnevsky et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
Sarah M. Williams et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
Junwei Shi et al.
MOLECULAR CELL (2014)
HDAC8 substrates: Histones and beyond
Noah A. Wolfson et al.
BIOPOLYMERS (2013)
BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure
Priti Anand et al.
CELL (2013)
Role of histone deacetylases in regulation of phenotype of ovine newborn pulmonary arterial smooth muscle cells
Q. Yang et al.
CELL PROLIFERATION (2013)
An Update on Medical Therapy for Pulmonary Arterial Hypertension
Yan Wu et al.
CURRENT HYPERTENSION REPORTS (2013)
Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition
Silvia Cantoni et al.
FEBS JOURNAL (2013)
BET acetyl-lysine binding proteins control pathological cardiac hypertrophy
Jessica I. Spiltoir et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group
Mercedes Lobera et al.
NATURE CHEMICAL BIOLOGY (2013)
HDAC-dependent ventricular remodeling
Min Xie et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2013)
Therapeutic Potential for HDAC Inhibitors in the Heart
Timothy A. McKinsey
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis
Danny Hung-Chieh Chou et al.
CHEMISTRY & BIOLOGY (2012)
Histone Deacetylation Inhibition in Pulmonary Hypertension Therapeutic Potential of Valproic Acid and Suberoylanilide Hydroxamic Acid
Lan Zhao et al.
CIRCULATION (2012)
Heart Disease and Stroke Statistics-2012 Update A Report From the American Heart Association
Veronique L. Roger et al.
CIRCULATION (2012)
Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism
Maria A. Cavasin et al.
CIRCULATION RESEARCH (2012)
Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries
Takayoshi Suzuki et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns
Alicia Lundby et al.
CELL REPORTS (2012)
New Models of Pulmonary Hypertension Based on VEGF Receptor Blockade-Induced Endothelial Cell Apoptosis
Mark R. Nicolls et al.
Pulmonary Circulation (2012)
Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats
Harm J. Bogaard et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
HDAC3-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor Activity
Sadhana A. Samant et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Acetylation of Heat Shock Protein 20 (Hsp20) Regulates Human Myometrial Activity
Magdalena Karolczak-Bayatti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension
Min Li et al.
JOURNAL OF IMMUNOLOGY (2011)
Isoform-selective HDAC inhibitors: Closing in on translational medicine for the heart
Timothy A. McKinsey
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension
Douglas D. Lemon et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin
Daniel M. Fass et al.
ACS MEDICINAL CHEMISTRY LETTERS (2011)
Sodium Valproate, a Histone Deacetylase Inhibitor, but Not Captopril, Prevents Right Ventricular Hypertrophy in Rats
Young Kuk Cho et al.
CIRCULATION JOURNAL (2010)
Protein Acetylation in the Cardiorenal Axis The Promise of Histone Deacetylase Inhibitors
Erik W. Bush et al.
CIRCULATION RESEARCH (2010)
Histone Deacetylases: Anti-Angiogenic Targets in Cancer Therapy
D. Mottet et al.
CURRENT CANCER DRUG TARGETS (2010)
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
Joo-Yong Lee et al.
EMBO JOURNAL (2010)
A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase
Lauren Monovich et al.
FEBS LETTERS (2010)
Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A
Kyle V. Butler et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
An Acetylation Switch Modulates the Transcriptional Activity of Estrogen-Related Receptor α
Brian J. Wilson et al.
MOLECULAR ENDOCRINOLOGY (2010)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Chemical phylogenetics of histone deacetylases
James E. Bradner et al.
NATURE CHEMICAL BIOLOGY (2010)
Inactivation of CREB mediated gene transcription by HDAC8 bound protein phosphatase
Jingxia Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Structure-function studies for the panacea, valproic acid
Nicole Terbach et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Studies of Benzamide- and Thiol-Based Histone Deacetylase Inhibitors in Models of Oxidative-Stress-Induced Neuronal Death: Identification of Some HDAC3-Selective Inhibitors
Yufeng Chen et al.
CHEMMEDCHEM (2009)
Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure
Harm J. Bogaard et al.
CIRCULATION (2009)
Targeting of HDAC8 and investigational inhibitors in neuroblastoma
Ina Oehme et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association
Vallerie V. McLaughlin et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
Nicholas W. Morrell et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
The Right Ventricle: Biologic Insights and Response to Disease
Lori A. Walker et al.
CURRENT CARDIOLOGY REVIEWS (2009)
Phenylglycine and phenylalanine derivatives as potent and selective (H)under-barDAC(1)over-cap (i)under-barnhibitors (SHI-1)
Kevin J. Wilson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Optimization of biaryl selective HDAC1&2 inhibitors (SHI-1&COLRATIO;2)
David J. Witter et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
Joey L. Methot et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber et al.
BMC MEDICINE (2008)
Eloquent silence: developmental functions of Class I histone deacetylases
Vincent T. Cunliffe
CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4
Johannes Backs et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions
Agustin Valenzuela-Fernandez et al.
TRENDS IN CELL BIOLOGY (2008)
Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity
Oscar M. Moradei et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration
Udai Bhan Pandey et al.
AUTOPHAGY (2007)
Unraveling the hidden catalytic activity of vertebrate class Ila histone deacetylases
A. Lahm et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
Dwayne A. Bisgrovet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey et al.
NATURE (2007)
Derepression of pathological cardiac genes by members of the CaM kinase superfamily
Timothy A. McKinsey
CARDIOVASCULAR RESEARCH (2007)
Histone deacetylase 3 localizes to the plasma membrane and is a substrate of Src
M. S. Longworth et al.
ONCOGENE (2006)
CaM kinase II selectively signals to histone deacetylase 4 during cardiornyocyte hypertrophy
Johannes Backs et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Regulation of cardiac stress signaling by protein kinase D1
Brooke C. Harrison et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin
A Iwata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
MK Jang et al.
MOLECULAR CELL (2005)
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein brd4
ZY Yang et al.
MOLECULAR CELL (2005)
Histone deacetylase HDAC8 associates with smooth muscle α-actin and is essential for smooth muscle cell contractility
D Waltregny et al.
FASEB JOURNAL (2005)
Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
IV Gregoretti et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Cellular and molecular pathobiology of pulmonary arterial hypertension
M Humbert et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Cyclin-dependent kinase-9 - An RNAPII kinase at the nexus of cardiac growth and death cascades
M Sano et al.
CIRCULATION RESEARCH (2004)
Subtype selective substrates for histone deacetylases
B Heltweg et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
RB Vega et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
SJ Haggarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
M Sano et al.
NATURE MEDICINE (2002)
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
CF Deroanne et al.
ONCOGENE (2002)
Enzymatic activity associated with class IIHDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
W Fischle et al.
MOLECULAR CELL (2002)
Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7
HY Kao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Identification of a signal-responsive nuclear export sequence in class II histone deacetylases
TA McKinsey et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
L Taraseviciene-Stewart et al.
FASEB JOURNAL (2001)
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
TA McKinsey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation
TA McKinsey et al.
NATURE (2000)
Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases
JR Lu et al.
MOLECULAR CELL (2000)
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization
CM Grozinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity
C Lemercier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
JR Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)