期刊
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
卷 34, 期 1, 页码 279-309出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14756366.2018.1545767
关键词
Tyrosinase; inhibitor; depigmentation agents; antibrowning compounds
资金
- Research Council of University of Tehran
- Research Council of IAU Jahrom Branch
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose, many natural, semi-synthetic and synthetic inhibitors have been developed by different screening methods to date. This review has focused on the tyrosinase inhibitors discovered from all sources and biochemically characterised in the last four decades.
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