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STIM1 and STIM2 differently regulate endogenous Ca2+ entry and promote TGF-β-induced EMT in breast cancer cells
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STIM2 enhances receptor-stimulated Ca2+ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions
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STIM2 enhances receptor-stimulated Ca2+ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions
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SCIENCE SIGNALING (2015)
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STIM1 regulates TRPC6 heteromultimerization and subcellular location
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STIM1-and Orail-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
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CD4+ and CD8+ T cell-dependent antiviral immunity requires STIM1 and STIM2
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A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration
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Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry
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PIGMENT CELL & MELANOMA RESEARCH (2014)
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site
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STIM1 negatively regulates Ca2+ release from the sarcoplasmic reticulum in skeletal myotubes
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Microtubule-Associated Histone Deacetylase 6 Supports the Calcium Store Sensor STIM1 in Mediating Malignant Cell Behaviors
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STIM1 and STIM2-mediated Ca2+ influx regulates antitumour immunity by CD8+ T cells
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EMBO MOLECULAR MEDICINE (2013)
The ER Ca2+ sensor STIM1 regulates actomyosin contractility of migratory cells
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STIM2 drives Ca2+ oscillations through store-operated Ca2+ entry caused by mild store depletion
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JOURNAL OF BIOMEDICAL SCIENCE (2013)
Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype
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MOLECULAR CARCINOGENESIS (2012)
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Jonathan Soboloff et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Different agonists recruit different stromal interaction molecule proteins to support cytoplasmic Ca2+ oscillations and gene expression
Pulak Kar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Di-Arginine Signals and the K-Rich Domain Retain the Ca2+ Sensor STIM1 in the Endoplasmic Reticulum
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TRAFFIC (2012)
The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production
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IMMUNITY (2011)
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
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NATURE REVIEWS DRUG DISCOVERY (2010)
Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis
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STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1
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CELL (2009)
An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal
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CELL (2009)
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Stromal Interaction Molecule (STIM) 1 and STIM2 Calcium Sensing Regions Exhibit Distinct Unfolding and Oligomerization Kinetics
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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CURRENT BIOLOGY (2008)
STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation
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FASEB JOURNAL (2008)
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
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METHODS (2008)
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels
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CELL (2007)
Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Orai1 and STIM reconstitute store-operated calcium channel function
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
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SCIENCE (2006)
STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels
MA Spassova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
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