期刊
ISRAEL JOURNAL OF CHEMISTRY
卷 58, 期 12, 页码 1315-1329出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ijch.201800051
关键词
polysaccharides; chitosan; alginate; cyclodextrin; nanoparticles; cancer; drug delivery
Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide-based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide-based nanoparticles as drug delivery tool for effective therapy and site-specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides-based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.
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