Chitosan-based embolizing hydrogel for the treatment of endoleaks after endovascular aneurysm repair

Persistent perfusion of the space between the stent-graft and the aneurysm wall (endoleak) is the most common failure mode of endovascular aneurysm repair. In this respect, several embolizing agents have been proposed for embolization of abdominal aortic aneurysms to avoid endoleaks. Among these, a chitosan-based embolizing hydrogel agent has been proposed and it is under investigation. This radiopaque hydrogel, which gels in situ and it is trackable in vivo, showed a great potential as embolizing agent for endovascular aneurysm repair and other endovascular therapies. [GRAPHICS] .