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Weight Loss after Gastric Bypass Surgery in Human Obesity Remodels Promoter Methylation
Romain Barres et al.
CELL REPORTS (2013)
A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue
Tina Ronn et al.
PLOS GENETICS (2013)
DNA methylation age of human tissues and cell types
Steve Horvath
GENOME BIOLOGY (2013)
Human T cell aging and the impact of persistent viral infections
T. Fueloep et al.
FRONTIERS IN IMMUNOLOGY (2013)
How ageing processes influence cancer
Joao Pedro de Magalhaes
NATURE REVIEWS CANCER (2013)
Dietary polyamine intake and risk of colorectal adenomatous polyps
Ashley J. Vargas et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2012)
Polyamines Induced by Osmotic Stress Protect Synechocystis sp PCC 6803 Cells and Arginine Decarboxylase Transcripts Against UV-B Radiation
Apiradee Pothipongsa et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2012)
Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria
Ines Sanchez-Roman et al.
BIOGERONTOLOGY (2012)
Effects of resveratrol on blood homocysteine level, on homocysteine induced oxidative stress, apoptosis and cognitive dysfunctions in rats
Sema Tulay Koz et al.
BRAIN RESEARCH (2012)
Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
Romain Barres et al.
CELL METABOLISM (2012)
Dendritic cells and aging: consequences for autoimmunity
Anshu Agrawal et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2012)
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial
Wendy N. Cooper et al.
FASEB JOURNAL (2012)
Age-associated DNA methylation in pediatric populations
Reid S. Alisch et al.
GENOME RESEARCH (2012)
Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities
Ana M. M. Oliveira et al.
NATURE NEUROSCIENCE (2012)
Age-associated chronic diseases require age-old medicine: Role of chronic inflammation
Sandeo Prasad et al.
PREVENTIVE MEDICINE (2012)
Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age
Mingcan Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Spermidine and Spermine Are Enriched in Whole Blood of Nona/Centenarians
Stefania Pucciarelli et al.
REJUVENATION RESEARCH (2012)
Crosstalk between aging and the epigenome
Hanneke Vlaming et al.
EPIGENOMICS (2012)
Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population
Jordana T. Bell et al.
PLOS GENETICS (2012)
Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells
Yung Hyun Choi et al.
JOURNAL OF BIOMEDICAL SCIENCE (2012)
NKG2D expression in CD4+T lymphocytes as a marker of senescence in the aged immune system
Rebeca Alonso-Arias et al.
AGE (2011)
Cognitive function after supplementation with B vitamins and long-chain omega-3 fatty acids: ancillary findings from the SU.FOL.OM3 randomized trial
Valentina A. Andreeva et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Spermine synthase activity affects the content of decarboxylated S-adenosylmethionine
Anthony E. Pegg et al.
BIOCHEMICAL JOURNAL (2011)
Mediterranean dietary pattern and cancer risk in the EPIC cohort
E. Couto et al.
BRITISH JOURNAL OF CANCER (2011)
Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands
Heather M. O'Hagan et al.
CANCER CELL (2011)
Methionine and homocysteine modulate the rate of ROS generation of isolated mitochondria in vitro
Jose Gomez et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart
Ines Sanchez-Roman et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
The mechanisms by which polyamines accelerate tumor spread
Kuniyasu Soda
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Richard A. Miller et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2011)
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
Camilla Burnett et al.
NATURE (2011)
Differential effects of nutritional folic acid deficiency and moderate hyperhomocysteinemia on aortic plaque formation and genome-wide DNA methylation in vascular tissue from ApoE-/- mice
Chris J. McNeil et al.
CLINICAL EPIGENETICS (2011)
Conformity to traditional Mediterranean diet and breast cancer risk in the Greek EPIC (European Prospective Investigation into Cancer and Nutrition) cohort
Antonia Trichopoulou et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)
Accruing evidence on benefits of adherence to the Mediterranean diet on health an updated systematic review and meta-analysis
Francesco Sofi et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction
Esther M. E. van Straten et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
DNA Condensation by Chiral alpha-Methylated Polyamine Analogues and Protection of Cellular DNA from Oxidative Damage
Irina Nayvelt et al.
BIOMACROMOLECULES (2010)
Soy Consumption and Colorectal Cancer Risk in Humans: A Meta-Analysis
Lin Yan et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)
Recent advances in the genetics of systemic lupus erythematosus
Donna L. Thibault Flesher et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2010)
Widespread and tissue specific age-related DNA methylation changes in mice
Shinji Maegawa et al.
GENOME RESEARCH (2010)
The effect of folic acid supplementation on carotid intima-media thickness in patients with cardiovascular risk: A randomized, placebo-controlled trial
George Ntaios et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2010)
Effects of Homocysteine-Lowering With Folic Acid Plus Vitamin B12 vs Placebo on Mortality and Major Morbidity in Myocardial Infarction Survivors A Randomized Trial
Jane M. Armitage et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial
G. J. Hankey et al.
LANCET NEUROLOGY (2010)
Perinatal folate supply: relevance in health outcome parameters
Katalin Fekete et al.
MATERNAL AND CHILD NUTRITION (2010)
Ornithine Decarboxylase Antizyme Induces Hypomethylation of Genome DNA and Histone H3 Lysine 9 Dimethylation (H3K9me2) in Human Oral Cancer Cell Line
Daisuke Yamamoto et al.
PLOS ONE (2010)
Prospective cohort study of soy food intake and colorectal cancer risk in women
Gong Yang et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Inflammatory cytokines in vascular dysfunction and vascular disease
Alexander H. Sprague et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Polyamine-rich food decreases age-associated pathology and mortality in aged mice
Kuniyasu Soda et al.
EXPERIMENTAL GERONTOLOGY (2009)
Polyamines: Potential anti-inflammatory agents and their possible mechanism of action
SureshRamnath Naik et al.
INDIAN JOURNAL OF PHARMACOLOGY (2009)
Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart
Jose Gomez et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2009)
Long-Term Oral Polyamine Intake Increases Blood Polyamine Concentrations
Kuniyasu Soda et al.
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Periconceptional Maternal Folic Acid Use of 400 μg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child
Regine P. Steegers-Theunissen et al.
PLOS ONE (2009)
A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease
Jae Hee Kang et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)
Epidemiology of soy exposures and breast cancer risk
A. H. Wu et al.
BRITISH JOURNAL OF CANCER (2008)
Conformity to traditional Mediterranean diet and cancer incidence: the Greek EPIC cohort
V. Benetou et al.
BRITISH JOURNAL OF CANCER (2008)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
Kevin J. Pearson et al.
CELL METABOLISM (2008)
Regulation of IGF-I function by proinflammatory cytokines: At the interface of immunology and endocrinology
Jason C. O'Connor et al.
CELLULAR IMMUNOLOGY (2008)
Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation
Po-Yuan Chang et al.
CIRCULATION RESEARCH (2008)
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study
Manon V. van Hecke et al.
CLINICAL SCIENCE (2008)
Dietary Intake of Soy Protein and Tofu in Association With Breast Cancer Risk Based on a Case-Control Study
Mi Kyung Kim et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2008)
Nutritional control of reproductive status in honeybees via DNA methylation
R. Kucharski et al.
SCIENCE (2008)
Inflammation and insulin resistance
Carl de Luca et al.
FEBS LETTERS (2008)
A Randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women - Results from the women's antioxidant cardiovascular study
Nancy R. Cook et al.
ARCHIVES OF INTERNAL MEDICINE (2007)
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide
J. E. Rider et al.
AMINO ACIDS (2007)
Polyamine contents in current foods: a basis for polyamine reduced diet and a study of its long term observance and tolerance in prostate carcinoma patients
B. G. Cipolla et al.
AMINO ACIDS (2007)
Amounts of polyamines in foods in Japan and intake by Japanese
Naoyoshi Nishibori et al.
FOOD CHEMISTRY (2007)
Soy product consumption and the risk of colon cancer: A prospective study in Takayama, Japan
Shino Oba et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2007)
Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes
Colin Selman et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria
Irina G. Sava et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins
Alberto Sanz et al.
FASEB JOURNAL (2006)
Meta-analysis of soy intake and breast cancer risk
BJ Trock et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Soy protein, isoflavones, and cardiovascular health - An American heart association science advisory for professionals from the nutrition committee
FM Sacks et al.
CIRCULATION (2006)
Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice
J Yan et al.
EXPERIMENTAL GERONTOLOGY (2006)
Diet quality is associated with the risk of estrogen receptor-negative breast cancer in postmenopausal women.
TT Fung et al.
JOURNAL OF NUTRITION (2006)
Decrease in polyamines with aging and their ingestion from food and drink
K Nishimura et al.
JOURNAL OF BIOCHEMISTRY (2006)
Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease
DJ Stott et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2005)
Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte
K Soda et al.
JOURNAL OF IMMUNOLOGY (2005)
Substrate-specific activation of sirtuins by resveratrol
M Kaeberlein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Antioxidative properties of natural polyamines and dimethylsilane analogues
F Gaboriau et al.
REDOX REPORT (2005)
Meta-analysis: High-dosage vitamin E supplementation may increase all-cause mortality
ER Miller et al.
ANNALS OF INTERNAL MEDICINE (2005)
Opposite effects of low and high dose supplementation of vitamin E on survival of MRL/lpr mice
CC Hsieh et al.
NUTRITION (2005)
Determinants of cofactor binding to DNA methyltransferases: insights from a systematic series of structural variants of S-adenosylhomocysteine
HM Cohen et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2005)
The impact of α-lipoic acid, coenzyme Q10, and caloric restriction on life span and gene expression patterns in mice
CK Lee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death - The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
JF Toole et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
The immunoregulatory effects of homocysteine and its intermediates on T-lymphocyte function
H Dawson et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2004)
Polyamines reduces lipid peroxidation induced by different pro-oxidant agents
NAV Bellé et al.
BRAIN RESEARCH (2004)
Homocysteine as a predictive factor for hip fracture in older persons
RR McLean et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Homocysteine levels and the risk of osteoporotic fracture
JBJ van Meurs et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Abnormal growth of polyamine-deficient Escherichia coli mutant is partially caused by oxidative stress-induced damage
IL Jung et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
MA Casillas et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Soy protein with or without isofleivones, soy germ and soy germ extract, and daidzein lessen plasma cholesterol levels in golden syrian hamsters
TT Song et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2003)
Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials
DP Vivekananthan et al.
LANCET (2003)
Rapid absorption of luminal polyamines in a rat small intestine ex vivo model
K Uda et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2003)
The polyamines sperimidine and spermidine protect proteins from structural and functional damage by AGE precursors: a new role for old molecules?
A Gugliucci et al.
LIFE SCIENCES (2003)
Polyamine-reduced diet in metastatic hormone-refractory prostate cancer (HRPC) patients
B Cipolla et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2003)
Polyamines protect Escherichia coli cells from the toxic effect of oxygen
MK Chattopadhyay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice
SD Chauhan et al.
FASEB JOURNAL (2003)
Soy consumption and colorectal cancer
D Spector et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2003)
Dietary arginine slightly and variably affects tissue polyamine levels in male Swiss albino mice
D Teixeira et al.
JOURNAL OF NUTRITION (2002)
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade
TS Weiss et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2002)
Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-κB
K La Ferla et al.
FASEB JOURNAL (2002)
Effects of dietary polyamines on the promotion of mammary tumor in rats
M Wada et al.
JOURNAL OF HEALTH SCIENCE (2002)
Role of DNA methylation in the regulation of cell function: Autoimmunity, aging and cancer
BC Richardson
JOURNAL OF NUTRITION (2002)
Elevation in S-adenosylhomocysteine and DNA hypomethylation:: Potential epigenetic mechanism for homocysteine-related pathology
SJ James et al.
JOURNAL OF NUTRITION (2002)
Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter
ZY Zhang et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2002)
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
QJ Lu et al.
ARTHRITIS AND RHEUMATISM (2002)
Is ageing associated with a shift in the balance between Type 1 and Type 2 cytokines in humans?
M Sandmand et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2002)
Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts
N Lopatina et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Lyon Diet Heart Study - Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association step I dietary pattern on cardiovascular disease
P Kris-Etherton et al.
CIRCULATION (2001)
Effects of dietary polyamine deficiency on Trypanosoma gambiense infection in rats
K Nishimura et al.
EXPERIMENTAL PARASITOLOGY (2001)
Induction of epithelial differentiation and DNA demethylation in hamster malignant oral keratinocyte by ornithine decarboxylase antizyme
T Tsuji et al.
ONCOGENE (2001)
Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells
Q Yuan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Lack of an effect of vitamin E on lifespan of mice
AA Morley et al.
BIOGERONTOLOGY (2001)
Soy protein and cardiovascular disease - A statement for healthcare professionals from the Nutrition Committee of the AHA
JW Erdman
CIRCULATION (2000)
DNA damage by 5-aminolevulinic and 4,5-dioxovaleric acids in the presence of ferritin
P Di Mascio et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
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