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ONCOGENE (2009)
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist
Daniel R. Rhodes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A CXCR4 Antagonist CTCE-9908 Inhibits Primary Tumor Growth and Metastasis of Breast Cancer
Eugene H. Huang et al.
JOURNAL OF SURGICAL RESEARCH (2009)
Characterization of functional roles of DRY motif in the 2nd intracellular loop of dopamine D2 and D3 receptors
Ju-Heon Kim et al.
ARCHIVES OF PHARMACAL RESEARCH (2008)
Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells
Yasuo Nagaoka et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)
Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core
Kimberly M. Bonger et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
The Wnt-5a-Derived Hexapeptide Foxy-5 Inhibits Breast Cancer Metastasis In vivo by Targeting Cell Motility
Annette Safholm et al.
CLINICAL CANCER RESEARCH (2008)
Epigenetic gene silencing in the Wnt pathway in breast cancer
George J. Klarmann et al.
EPIGENETICS (2008)
The endothelin axis in cancer
Anna Bagnato et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Biology of somatostatin in breast cancer
Heather L. Watt et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)
Crystal structure of opsin in its G-protein-interacting conformation
Patrick Scheerer et al.
NATURE (2008)
Selective ETAR antagonist atrasentan inhibits hypoxia-induced breast cancer cell invasion
M. Smollich et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
Zhongxing Liang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Triple-negative breast cancer: Clinical features and patterns of recurrence
Rebecca Dent et al.
CLINICAL CANCER RESEARCH (2007)
Luteinizing hormone-releasing hormone agonists in premenopausal hormone receptor-positive breast cancer
Sing-Huang Tan et al.
CLINICAL BREAST CANCER (2007)
Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone
Joerg B. Engel et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2007)
G-protein-coupled receptors and cancer
Robert T. Dorsam et al.
NATURE REVIEWS CANCER (2007)
The highly conserved DRY motif of class A G protein-coupled receptors: Beyond the ground state
G. Enrico Rovati et al.
MOLECULAR PHARMACOLOGY (2007)
MicroPET imaging of breast cancer using radiolabeled bombesin analogs targeting the gastrin-releasing peptide receptor
Jesse J. Parry et al.
BREAST CANCER RESEARCH AND TREATMENT (2007)
Peptide Receptor Radionuclide Therapy with radiolabelled somatostatin analogues in patients with somatostatin receptor positive tumours
Martijn Van Essen et al.
ACTA ONCOLOGICA (2007)
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: A potential novel mechanism of endocrine disruption
Peter Thomas et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2006)
Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism
Li Yang et al.
CANCER RESEARCH (2006)
17β-Estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein-coupled receptor GPR30
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MOLECULAR PHARMACOLOGY (2006)
Gastrin-releasing peptide and cancer
Oneel Patel et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2006)
Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer
M. Z. Dewan et al.
BIOMEDICINE & PHARMACOTHERAPY (2006)
Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Gonadotropin-releasing hormone (GnRH) receptors in tumors: a new rationale for the therapeutical application of GnRH analogs in cancer patients?
M. Montagnani Marelli et al.
CURRENT CANCER DRUG TARGETS (2006)
COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer
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BRITISH JOURNAL OF CANCER (2006)
Virtual and biomolecular screening converge on a selective agonist for GPR30
CG Bologa et al.
NATURE CHEMICAL BIOLOGY (2006)
Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis
XR Ma et al.
CANCER RESEARCH (2006)
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells
A Vivacqua et al.
MOLECULAR ENDOCRINOLOGY (2006)
Mammalian G proteins and their cell type specific functions
N Wettschureck et al.
PHYSIOLOGICAL REVIEWS (2005)
Use of goserelin in the treatment of breast cancer
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EXPERT REVIEW OF ANTICANCER THERAPY (2005)
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARγ, and inhibitors of autotaxin
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JOURNAL OF MEDICINAL CHEMISTRY (2005)
Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-1I, and their receptors in humans
CK Cheng et al.
ENDOCRINE REVIEWS (2005)
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
CM Revankar et al.
SCIENCE (2005)
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells
A Boire et al.
CELL (2005)
Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer
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CLINICAL CANCER RESEARCH (2004)
Gonadotropin-releasing hormone receptors
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ENDOCRINE REVIEWS (2004)
Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonists
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JOURNAL OF MEDICINAL CHEMISTRY (2004)
Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor - Transfer of binding site to the CXCR3 receptor
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of Endothelin-A-Receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer
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BRITISH JOURNAL OF CANCER (2004)
CXCR4 regulates growth of both primary and metastatic breast cancer
MCP Smith et al.
CANCER RESEARCH (2004)
The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
ZX Liang et al.
CANCER RESEARCH (2004)
Renin-angiotensin system blockade at the level of the angiotensin converting enzyme or the angiotensin type-1 receptor: Similarities and differences
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CURRENT TOPICS IN MEDICINAL CHEMISTRY (2004)
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ki16425, a subtype-selective antagonist for EDG-Family lysophosphatidic acid receptors
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MOLECULAR PHARMACOLOGY (2003)
T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer
H Tamamura et al.
FEBS LETTERS (2003)
Human protease-activated receptor 1 expression in malignant epithelia - A role in invasiveness
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ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: A concise update
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NUCLEAR MEDICINE AND BIOLOGY (2003)
Designing peptide receptor agonists and antagonists
VJ Hruby
NATURE REVIEWS DRUG DISCOVERY (2002)
A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C axe weak partial agonists
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells
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JOURNAL OF ENDOCRINOLOGY (2002)
A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP1 antagonist, on breast cancer development
T Kawamori et al.
CARCINOGENESIS (2001)
Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140
H Tamamura et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
Involvement of chemokine receptors in breast cancer metastasis
A Müller et al.
NATURE (2001)
Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: A meta-analysis of four randomized trials
JGM Klijn et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
Is there a role for agonist gastrin-releasing peptide receptor radioligands in tumour imaging?
C Van de Wiele et al.
NUCLEAR MEDICINE COMMUNICATIONS (2001)
Antiproliferative effect of somatostatin and analogs
C Bousquet et al.
CHEMOTHERAPY (2001)
Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate
AL Parrill et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Targeting delivery of paclitaxel into tumor cells via somatostatin receptor endocytosis
CM Huang et al.
CHEMISTRY & BIOLOGY (2000)
β-catenin, a novel prognostic marker for breast cancer:: Its roles in cyclin D1 expression and cancer progression
SY Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Role of the highly conserved Asp-Arg-Tyr motif in signal transduction of the CB2 cannabinoid receptor
MH Rhee et al.
FEBS LETTERS (2000)
Signal transduction from the angiotensin II AT(2) receptor
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2000)
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