相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Advances in Evaluation of Chronic Diarrhea in Infants
Jay R. Thiagarajah et al.
GASTROENTEROLOGY (2018)
A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor
Jana Ylva Tretter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation
Sannia Sarrach et al.
SCIENTIFIC REPORTS (2018)
EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion
Aljaz Gaber et al.
SCIENTIFIC REPORTS (2018)
EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers
Min Pan et al.
PLOS BIOLOGY (2018)
Personalized medicine in colorectal cancer diagnosis and treatment: a systematic review of health economic evaluations
Annamaria Guglielmo et al.
COST EFFECTIVENESS AND RESOURCE ALLOCATION (2018)
Cytoplasmic MSH2 immunoreactivity in a patient with Lynch syndrome with an EPCAM-MSH2 fusion
Shigeki Sekine et al.
HISTOPATHOLOGY (2017)
Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients with Intestinal Failure
Sung Noh Hong et al.
STEM CELLS TRANSLATIONAL MEDICINE (2017)
Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis
Chuan-Jin Wu et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Advances in ligase chain reaction and ligation-based amplifications for genotyping assays: Detection and applications
Abdullah A. Gibriel et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2017)
Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification
Shimeng Fang et al.
PLOS ONE (2017)
New EPCAM founder deletion in Polish population
D. Dymerska et al.
CLINICAL GENETICS (2017)
Genomic analysis of an infant with intractable diarrhea and dilated cardiomyopathy
Dale L. Bodian et al.
COLD SPRING HARBOR MOLECULAR CASE STUDIES (2017)
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
Benedito Mauro Rossi et al.
BMC CANCER (2017)
Genetic analysis of Italian patients with congenital tufting enteropathy
Maria d'Apolito et al.
WORLD JOURNAL OF PEDIATRICS (2016)
A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair
Richard D. Kolodner
DNA REPAIR (2016)
A New Class of Antibody-Drug Conjugates with Potent DNA Alkylating Activity
Michael L. Miller et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Gene and splicing therapies for neuromuscular diseases
Aurelie Goyenvalle
Frontiers in Bioscience-Landmark (2015)
Cleavage and Cell Adhesion Properties of Human Epithelial Cell Adhesion Molecule (HEPCAM)
Thanos Tsaktanis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
MMTV/LTR Promoter-Driven Transgenic Expression of EpCAM Leads to the Development of Large Pancreatic Islets
Jeffrey R. Vercollone et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2015)
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
Adam Shlien et al.
NATURE GENETICS (2015)
Lynch-like syndrome: Characterization and comparison with EPCAM deletion carriers
So Young Kang et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction
Philip A. Kozan et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
A Novel Compound-Heterozygous Epithelial Cell Adhesion Molecule Mutation in Tufting Enteropathy
Valentina Shakhnovich et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2014)
Functional consequences of EpCam mutation in mice and men
James L. Mueller et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
Features of Gastric and Colonic Mucosa in Congenital Enteropathies A Study in Histology and Immunohistochemistry
Jitsupa Treetipsatit et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2014)
Tufting Enteropathy Revisited The Utility of MOC31 (EpCAM) Immunohistochemistry in Diagnosis
Sarangarajan Ranganathan et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2014)
Identification of a founder EPCAM deletion in Spanish Lynch syndrome families
P. Mur et al.
CLINICAL GENETICS (2014)
Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the U.S. Multi-Society Task Force on Colorectal Cancer
Francis M. Giardiello et al.
GASTROINTESTINAL ENDOSCOPY (2014)
Genetic characterization of congenital tufting enteropathy: epcam associated phenotype and involvement of SPINT2 in the syndromic form
Julie Salomon et al.
HUMAN GENETICS (2014)
A Novel Nonsense Mutation in the EpCAM Gene in a Patient With Congenital Tufting Enteropathy
Cornelia Thoeni et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2014)
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
Kaja Lund et al.
MABS (2014)
Crystal structure and its bearing towards an understanding of key biological functions of EpCAM
Miha Pavsic et al.
NATURE COMMUNICATIONS (2014)
EPCAM germline and somatic rearrangements in lynch syndrome: identification of a novel 3′EPCAM deletion
Marijke Spaepen et al.
GENES CHROMOSOMES & CANCER (2013)
Absence of cell-surface EpCAM in congenital tufting enteropathy
Ulrike Schnell et al.
HUMAN MOLECULAR GENETICS (2013)
Usefulness of epithelial cell adhesion molecule expression in the algorithmic approach to Lynch syndrome identification
Eva Musulen et al.
HUMAN PATHOLOGY (2013)
Epithelial Cell Adhesion Molecule (EpCAM) Regulates Claudin Dynamics and Tight Junctions
Chuan-Jin Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Colorectal cancer in a 9-year-old due to combined EPCAM and MSH2 germline mutations: case report of a unique genotype and immunophenotype
Hector H. Li-Chang et al.
JOURNAL OF CLINICAL PATHOLOGY (2013)
EpCAM regulates cell cycle progression via control of cyclin D1 expression
A. Chaves-Perez et al.
ONCOGENE (2013)
EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins
Zili Lei et al.
DEVELOPMENTAL BIOLOGY (2012)
Therapeutic Potential of Amanitin-Conjugated Anti-Epithelial Cell Adhesion Molecule Monoclonal Antibody Against Pancreatic Carcinoma
Gerhard Moldenhauer et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2012)
The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors
Cathrin Huth et al.
MODERN PATHOLOGY (2012)
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
Ryszard Kole et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
mTrop1/Epcam Knockout Mice Develop Congenital Tufting Enteropathy through Dysregulation of Intestinal E-cadherin/β-catenin
Emanuela Guerra et al.
PLOS ONE (2012)
Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo
Maria R. Gaiser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
EpCAM and its potential role in tumor-initiating cells
Sannia Imrich et al.
CELL ADHESION & MIGRATION (2012)
Lynch Syndrome-Associated Extracolonic Tumors Are Rare in Two Extended Families With the Same EPCAM Deletion
Henry T. Lynch et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2011)
Alu in Lynch Syndrome: A Danger SINE?
Megan P. Hitchins et al.
CANCER PREVENTION RESEARCH (2011)
Frequency of Rearrangements in Lynch Syndrome Cases Associated With MSH2: Characterization of a New Deletion Involving both EPCAM and the 5′ Part of MSH2
Lucia Perez-Cabornero et al.
CANCER PREVENTION RESEARCH (2011)
A founder effect at the EPCAM locus in Congenital Tufting Enteropathy in the Arabic Gulf
Julie Salomon et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2011)
Recurrence and Variability of Germline EPCAM Deletions in Lynch Syndrome
Roland P. Kuiper et al.
HUMAN MUTATION (2011)
Analysis of EPCAM Protein Expression in Diagnostics of Lynch Syndrome
Matthias Kloor et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Frequency of Deletions of EPCAM (TACSTD1) in MSH2-Associated Lynch Syndrome Cases
Kandelaria Rumilla et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2011)
Intractable Diarrhea With Tufting Enteropathy: A Favorable Outcome Is Possible
Julie Lemale et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2011)
Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study
Marlies J. E. Kempers et al.
LANCET ONCOLOGY (2011)
Alu elements: know the SINEs
Prescott Deininger
GENOME BIOLOGY (2011)
Further Evidence for EpCAM as the Gene for Congenital Tufting Enteropathy
Mamata Sivagnanam et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2010)
Somatic Hypermethylation of MSH2 Is a Frequent Event in Lynch Syndrome Colorectal Cancers
Takeshi Nagasaka et al.
CANCER RESEARCH (2010)
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
Yimin Hua et al.
GENES & DEVELOPMENT (2010)
Tufting Enteropathy with EpCAM Mutations in Two Siblings
Jae Sung Ko et al.
GUT AND LIVER (2010)
EPCAM Germ Line Deletions as Causes of Lynch Syndrome in Spanish Patients
Carla Guarinos et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2010)
Catumaxomab Clinical development and future directions
Rolf Linke et al.
MABS (2010)
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
H. T. Lynch et al.
CLINICAL GENETICS (2009)
Germline Hypermethylation of MLH1 and EPCAM Deletions Are a Frequent Cause of Lynch Syndrome
Renee C. Niessen et al.
GENES CHROMOSOMES & CANCER (2009)
Deletions Removing the Last Exon of TACSTD1 Constitute a Distinct Class of Mutations Predisposing to Lynch Syndrome
Marietta E. Kovacs et al.
HUMAN MUTATION (2009)
EpCAM is overexpressed in gastric cancer and its downregulation suppresses proliferation of gastric cancer
Du Wenqi et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2009)
Tufting Enteropathy and Chronic Arthritis: A Newly Recognized Association With a Novel EpCAM Gene Mutation
Sulaiman M. Al-Mayouf et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2009)
Nuclear signalling by tumour-associated antigen EpCAM
Dorothea Maetzel et al.
NATURE CELL BIOLOGY (2009)
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3 ' exons of TACSTD1
Marjolijn J. L. Ligtenberg et al.
NATURE GENETICS (2009)
Abnormal Placental Development and Early Embryonic Lethality in EpCAM-Null Mice
Keisuke Nagao et al.
PLOS ONE (2009)
EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype
Barbara Gonzalez et al.
STEM CELLS (2009)
The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish Epiboly and Skin Development
Krasimir Slanchev et al.
PLOS GENETICS (2009)
Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in Transgenic mice
Yimin Hua et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Identification of EpCAM as the gene for congenital tufting enteropathy
Mamata Sivagnanam et al.
GASTROENTEROLOGY (2008)
Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?
Katharina Wimmer et al.
HUMAN GENETICS (2008)
Expression of EpCAM is up-regulated during regeneration of renal epithelia
M. Trzpis et al.
JOURNAL OF PATHOLOGY (2008)
Inhibition of DNA methylation by antisense oligonucleotide MG98 as cancer therapy
Robert J. Amato
CLINICAL GENITOURINARY CANCER (2007)
Epithelial cell adhesion molecule - More than a carcinoma marker and adhesion molecule
Monika Trzpis et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Intestinal epithelial dysplasia (tufting enteropathy)
Olivier Goulet et al.
ORPHANET JOURNAL OF RARE DISEASES (2007)
Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer
Gilbert Spizzo et al.
GYNECOLOGIC ONCOLOGY (2006)
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
Tsun Leung Chan et al.
NATURE GENETICS (2006)
Control of cell migration in the zebrafish lateral line:: Implication of the gene tumour-associated calcium signal transducer, tacstd
Eduardo J. Villablanca et al.
DEVELOPMENTAL DYNAMICS (2006)
Serum antibodies to EpCAM in healthy donors but not ulcerative colitis patients
EE Furth et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2006)
Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome
KM Schmeler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers
P Went et al.
BRITISH JOURNAL OF CANCER (2006)
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary Nonpolyposis colorectal cancer (HNPCC)
H van der Klift et al.
GENES CHROMOSOMES & CANCER (2005)
The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7
M Ladwein et al.
EXPERIMENTAL CELL RESEARCH (2005)
Loss of Ep-CAM (CO17-1A) expression predicts survival in patients with gastric cancer
I Songun et al.
BRITISH JOURNAL OF CANCER (2005)
Expression of epithelial cell adhesion molecule (EpCam) in renal epithelial tumors
P Went et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2005)
Epithelial cell adhesion molecule (KSA) expression: Pathobiology and its role as an independent predictor of survival in renal cell carcinoma
DB Seligson et al.
CLINICAL CANCER RESEARCH (2004)
Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics
LE Maquat
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy
WA Osta et al.
CANCER RESEARCH (2004)
High Ep-CAM expression is associated with poor prognosis in node-positive breast cancer
G Spizzo et al.
BREAST CANCER RESEARCH AND TREATMENT (2004)
The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation
M Münz et al.
ONCOGENE (2004)
Frequent EpCam protein expression in human carcinomas
PT Went et al.
HUMAN PATHOLOGY (2004)
Neonatal enteropathies: Defining the causes of protracted diarrhea of infancy
PM Sherman et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2004)
Overexpression of epithelial cell adhesion molecule antigen in gallbladder carcinoma is an independent marker for poor survival
M Varga et al.
CLINICAL CANCER RESEARCH (2004)
Expression of Ep-CAM shifts the state of cadherin-mediated adhesions from strong to weak
MJ Winter et al.
EXPERIMENTAL CELL RESEARCH (2003)
Inhibition of DNA methylation and reactivation of silenced genes by zebularine
JC Cheng et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)
Isolated small bowel transplantation for tufting enteropathy
AS Paramesh et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2003)
Allelic and locus heterogeneity in autosomal recessive gelatinous drop-like corneal dystrophy
ZX Ren et al.
HUMAN GENETICS (2002)
Protracted diarrhea: Results of the five-year survey in a tertiary hospital in Korea
NS Beck et al.
JOURNAL OF KOREAN MEDICAL SCIENCE (2001)
分享论文
