期刊
EXPERIMENTAL PHYSIOLOGY
卷 104, 期 7, 页码 1013-1017出版社
WILEY
DOI: 10.1113/EP087424
关键词
cerebral circulation; cerebrospinal fluid; glymphatic; interstitial fluid; pulsatility
类别
资金
- Alzheimer Nederland
The interstitial fluid of the brain provides the environment for proper neuronal function. Maintenance of the volume and composition of interstitial fluid requires regulation of the influx and removal of water, ions, nutritive and waste products. The recently described glymphatic pathway might contribute to some of these functions. It is proposed that cerebrospinal fluid enters the brain via paravascular spaces along arteries, mixes with interstitial fluid, and leaves the brain via paravascular spaces along veins. In this symposium report, we review the glymphatic concept, its concerns, and alternative views on interstitial fluid-cerebrospinal fluid exchange.
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