期刊
EPILEPSY & BEHAVIOR
卷 90, 期 -, 页码 132-136出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yebeh.2018.11.015
关键词
Caregivers; Psychological comorbidity; Adult; Patients with epilepsy; Quality of life
资金
- Henan Provincial Science and Technology Agency [162102410041]
- Health and Family Planning Commission of Henan Province [201702208]
- Basic and Frontier technological Project in Henan Province [152300410155]
Objective: The objective of this study was to assess the anxiety and depression of caregivers of adult patients with epilepsy (PWE) and evaluate its effect on patient quality of life (QOL). Method: One hundred sixty pairs of adult PWE and their caregivers were enrolled in our study. Quality of life in adult PWE was evaluated with the Quality of Life in Epilepsy Inventory-31 scale (QOUE-31). Symptoms of anxiety and depression in caregivers were assessed with the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Rating Scale (HAM-D) respectively. Correlation and stepwise multiple liner regression analyses were used as statistical analysis. Results: Of the caregivers, 41 (31.30%) had anxiety symptoms (HAM-A scores> 6) and 44 (33.59%) had depression symptoms (HAM-D scores> 6). Caregiver anxiety was significantly associated with poorer adult PWE QOL scores in four of the seven subscales and the QOLIE-31 total score. Caregiver depression was significantly associated with poorer adult PWE QOL in all seven subscales as well as the QOLIE-31 total score. Caregiver depression was an independent predictor of the QOLIE-31 total score and five subscales: seizure worry, emotional wellbeing, energy/fatigue, cognitive, and medication effects. Conclusion: Caregivers of adult PWE are at high risk of experiencing anxiety and depression. Caregiver psychological status, especially depression, was an independent predictor of poorer QOL for adult PWE. (C) 2018 Elsevier Inc. All rights reserved.
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