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Cell Biology: Functional Conservation, Structural Divergence, and Surprising Convergence in the MICOS Complex of Trypanosomes

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CURRENT BIOLOGY
卷 28, 期 21, 页码 R1245-R1248

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CELL PRESS
DOI: 10.1016/j.cub.2018.09.057

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The MICOS complex is conserved across eukaryotes, but little is known about it outside the group that comprises animals and fungi. A new study finds that mitochondria of trypanosomatid parasites bear a divergent MICOS with both ancestral and derived subunits, but with conserved functions in crista development and membrane contact-site formation.

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