期刊
CRITICAL CARE CLINICS
卷 35, 期 1, 页码 61-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccc.2018.08.009
关键词
Heart transplantation; Lung transplantation; Acute kidney injury; Dialysis; Continuous renal replacement therapy
Renal complications are common following heart and/or lung transplantation and lead to increased morbidity and mortality. Renal dysfunction is also associated with increased mortality for patients on the transplant wait list. Dialysis dependence is a relative contraindication for heart or lung transplantation at most centers, and such patients are often listed for a simultaneous kidney transplant. Several factors contribute to the impaired renal function in patients undergoing heart and/or lung transplantation, including the interplay between cardiopulmonary and renal hemo-dynamics, complex perioperative issues, and exposure to nephrotoxic medications, mainly calcineurin inhibitors.
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