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Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management

期刊

EPMA JOURNAL
卷 6, 期 -, 页码 -

出版社

SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1186/s13167-015-0038-y

关键词

7 Tesla; Ultrahigh field MRI; Multiple sclerosis; Neuromyelitis optica; Susac syndrome; Neuroimmunology; Central vein sign; Cortical lesions; Predictive; Preventive and Personalised Medicine

资金

  1. German Research Foundation [DFG Exc 257]
  2. German Ministry of Education and Research (Competence Network Multiple Sclerosis KKNMS)
  3. Guthy Jackson Charitable Foundation/National Multiple Sclerosis Society of the USA

向作者/读者索取更多资源

Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility effects and improved SNR, ultrahigh field MRI at 7 T depicts inflammatory brain lesions in great detail. This review summarises recent reports on 7 T MRI in neuroinflammatory diseases and addresses the question as to whether ultrahigh field MRI may eventually improve clinical decision-making and personalised disease management.

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