期刊
CHINESE CHEMICAL LETTERS
卷 30, 期 4, 页码 863-866出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2018.10.040
关键词
Porous graphene; Hydrophilic interaction chromatography; Stationary phase; Sulfonamides; Human serum samples
资金
- National Natural Science Foundation of China [21822407, 21675164]
- funds for Distinguished Young Scientists of Gansu [1506RJDA281]
Porous graphene (PG) has potential applications in numerous fields because of the existence of nanopores in the plane. In this study, porous graphene decorated silica microspheres (Sil-PG) were successfully fabricated by assembling PG onto the silica particles surface in deep eutectic solvents (DESs). Experimental results demonstrate that this new stationary phase can facilitate the separation of six sulfonamides compounds in hydrophilic chromatographic conditions. The successful synthesis of the Sil-PG stationary phase provides a basis for the application of porous graphene-modified materials as the stationary phase for liquid chromatography, and offers the possibility to broaden the application of PG in the field of chromatography. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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