期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 24, 期 70, 页码 18676-18681出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201803151
关键词
bile acid amides; CPMAS NMR; gels; supramolecular gels; X-ray diffraction
资金
- Ellen and Artturi Nyyssonen Foundation
- Academy of Finland [298817]
- University of Jyvaskyla
The self-assembly properties of nine low-molecular-weight gelators (LMWGs) based on bile acid alkyl amides were studied in detail. Based on the results, the number of hydroxyl groups attached to the steroidal backbone plays a major role in the gelation, although the nature of the aliphatic side chain also modulates the gelation abilities. Of the 50 gel systems studied, 35 are based on lithocholic acid and 15 on cholic acid derivatives. The deoxycholic acid derivatives did not form any gels. The gelation occurred primarily in aromatic solvents and the gels manifested typical fibrous or spherical morphologies. The C-13 cross-polarized magic angle spinning (CPMAS) NMR spectra measured on the crystalline materials and the corresponding wet organogels were analogous, suggesting that the chemical environments, that is, the intermolecular interactions found in the two materials were similar. The single-crystal X-ray structures of all nine bile-acid amide derivatives studied revealed very similar molecular conformations in the solid state and gave insights into the possible intermolecular interactions in the gel state.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据