期刊
SLEEP
卷 38, 期 3, 页码 473-478出版社
OXFORD UNIV PRESS INC
DOI: 10.5665/sleep.4512
关键词
adverse event; deep brain stimulation; insomnia; sleep
资金
- Association pour la recherche sur la stimulation cerebrale-ARSC, ARSC Foundation
Study Objectives: To explore the influence of acute bilateral ventral intermediate thalamic nucleus (VIM) stimulation on sleep. Design: Three consecutive full-night polysomnography recordings were made in the laboratory. After the habituation night, a random order for night ON-stim and OFF-stim was applied for the second and third nights. Setting: Sleep disorders unit of a university hospital. Patients: Eleven patients with bilateral stimulation of the ventral intermediate nucleus of the thalamus (VIM) for drug-resistant tremor. Measurements: Sleep measures on polysomnography. Results: Total sleep time was reduced during night ON-stim compared to OFF-stim, as well as rapid eye movement sleep percentage while the percentage of N2 increased. Wakefulness after sleep onset time was increased. Conclusion: Our results show that bilateral stimulation of the VIM nuclei reduces sleep and could be associated with insomnia.
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