期刊
CHEMICAL RECORD
卷 19, 期 10, 页码 2105-2118出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201800168
关键词
Imidazo[1; 2-a]pyridines; Carbene transformations; C-H functionalizations; Multicomponent reactions
资金
- Innovation and Strong School Project of Guangdong Pharmaceutical University [2015cxqx212]
- Science and Technology Planning Project of Guangzhou [201806040009, 201804010349]
- Industry University Research Collaborative Innovation Major Projects of Guangzhou Science Technology Innovation Commission, China [201604020164]
- Guangdong Provincial University Engineering Technology Research Center of Natural Products and Drugs [2017GCZX002]
- Provincial Experimental Teaching Demonstration Center of Chemistry & Chemical Engineering
- Guangdong Cosmetics Engineering & Technology Research Center
The imidazo[1,2-a]pyridines are an important target in organic synthetic chemistry and have attracted critical attention of chemists mainly due to the discovery of the interesting properties exhibited by a great number of imidazo[1,2-a]pyridine derivatives. Although lots of synthetic methods of imidazo[1,2-a]pyridines have been developed in the past years, the chemistry community faces continuing challenges to use green reagents, maximize atom economy and enrich the functional group diversity of product. Undoubtedly, with its low cost and lack of environmentally hazardous byproducts, cascade reactions and C-H functionalizations are ideal strategies for this field. In this record we highlight some of our progress toward the goal to synthesis of imidazo[1,2-a]pyridine derivatives through carbene transformations or C-H functionalizations.
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