期刊
CHEMCATCHEM
卷 11, 期 1, 页码 435-438出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cctc.201801601
关键词
C-H activation; Deuterium labelling; Ruthenium; Carboxylate assistance; Hydrogen isotope exchange (HIE)
资金
- DFG
- European Research Council under the European Community [307535]
Ruthenium(II) biscarboxylate catalysis enabled efficient hydrogen isotope exchange of acrylic C-H bonds with user-friendly D2O. The C-H labelling was characterized by excellent positional selectivity and a broad functional group tolerance. The deuteration was successfully conducted on 55mmol scale with TONs of >1000, while mechanistic studies provided insights into ruthenium(II) oxidase catalysis. The obtained deuterated alkenes enabled the synthesis of labeled standards for mass spectrometry of irradiated foodstuffs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据