相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Tubulin Posttranslational Modifications and Emerging Links to Human Disease
Maria M. Magiera et al.
CELL (2018)
Hedgehog Antagonist Pyrimidine-Indole Hybrid Molecule Inhibits Ciliogenesis through Microtubule Destabilisation
Harleen Khatra et al.
CHEMBIOCHEM (2018)
Tubulin acetylation protects long-lived microtubules against mechanical ageing
Didier Portran et al.
NATURE CELL BIOLOGY (2017)
Genes and molecular pathways underpinning ciliopathies
Jeremy F. Reiter et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Microtubules acquire resistance from mechanical breakage through intralumenal acetylation
Zhenjie Xu et al.
SCIENCE (2017)
Causes and Consequences of Microtubule Acetylation
Carsten Janke et al.
CURRENT BIOLOGY (2017)
Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation
Hankyu Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction
Tatiana Gorojankina
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy
Ekaterina Pak et al.
DEVELOPMENTAL CELL (2016)
Metabolic regulation of mitochondrial dynamics
Prashant Mishra et al.
JOURNAL OF CELL BIOLOGY (2016)
Control of inflammation by stromal Hedgehog pathway activation restrains colitis
John J. Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance
Wolfgang Gruber et al.
ONCOTARGET (2016)
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome
Arnaud Duchon et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2016)
Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1
Philipp Schneider et al.
NATURE COMMUNICATIONS (2015)
DYRK1B variant linked to autosomal dominant metabolic syndrome
J. Hickmott
CLINICAL GENETICS (2015)
Phosphorylation and Inactivation of Glycogen Synthase Kinase 3β (GSK3β) by Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A)
Woo-Joo Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Histone Deacetylase 6 Represents a Novel Drug Target in the Oncogenic Hedgehog Signaling Pathway
Pavan Kumar Dhanyamraju et al.
MOLECULAR CANCER THERAPEUTICS (2015)
A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr286, not Thr288
Anne L. Ashford et al.
BIOCHEMICAL JOURNAL (2014)
Interplay Between HDAC6 and Its Interacting Partners: Essential Roles in the Aggresome-Autophagy Pathway and Neurodegenerative Diseases
Jin Yan
DNA AND CELL BIOLOGY (2014)
The tubulin code: Molecular components, readout mechanisms, and functions
Carsten Janke
JOURNAL OF CELL BIOLOGY (2014)
A Form of the Metabolic Syndrome Associated with Mutations in DYRK1B
Ali R. Keramati et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy
Fritz Aberger et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production
Bin Wang et al.
NATURE COMMUNICATIONS (2014)
The Yes-associated protein controls the cell density regulation of Hedgehog signaling
M. Tariki et al.
ONCOGENESIS (2014)
Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
Norihiko Sakai et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
Mitochondrial Localization and the Persistent Migration of Epithelial Cancer cells
Salil P. Desai et al.
BIOPHYSICAL JOURNAL (2013)
RIO kinase 3 acts as a SUFU-dependent positive regulator of Hedgehog signaling
Melanie Tariki et al.
CELLULAR SIGNALLING (2013)
Mirk/dyrk1B Kinase in Ovarian Cancer
Eileen Friedman
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
αTAT1 catalyses microtubule acetylation at clathrin-coated pits
Guillaume Montagnac et al.
NATURE (2013)
The mechanisms of Hedgehog signalling and its roles in development and disease
James Briscoe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse
Maike de la Roche et al.
SCIENCE (2013)
Hdac6 regulates Tip60-p400 function in stem cells
Poshen B. Chen et al.
ELIFE (2013)
Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
Loredana Santo et al.
BLOOD (2012)
Mitochondrial dynamics and their impact on T cell function
Ariel Quintana et al.
CELL CALCIUM (2012)
The axonal transport of mitochondria
William M. Saxton et al.
JOURNAL OF CELL SCIENCE (2012)
Tubulin Acetylation Alone Does Not Affect Kinesin-1 Velocity and Run Length In Vitro
Wilhelm J. Walter et al.
PLOS ONE (2012)
Hedgehog-Stimulated Chemotaxis Is Mediated by Smoothened Located Outside the Primary Cilium
Maarten F. Bijlsma et al.
SCIENCE SIGNALING (2012)
The Hedgehog Signal Transduction Network
David J. Robbins et al.
SCIENCE SIGNALING (2012)
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation
Anthony B. Mak et al.
CELL REPORTS (2012)
Gli Proteins in Development and Disease
Chi-chung Hui et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Heterotrimeric Gi Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration
Ariel H. Polizio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics
Claudia Dafinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
Kunyoo Shin et al.
NATURE (2011)
Sonic Hedgehog Activates the GTPases Rac1 and RhoA in a Gli-Independent Manner Through Coupling of Smoothened to Gi Proteins
Ariel H. Polizio et al.
SCIENCE SIGNALING (2011)
Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation
Nobunari Sasaki et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Posttranslational Modifications of Tubulin and the Polarized Transport of Kinesin-1 in Neurons
Jennetta W. Hammond et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
MEC-17 is an α-tubulin acetyltransferase
Jyothi S. Akella et al.
NATURE (2010)
The primary cilium: a signalling centre during vertebrate development
Sarah C. Goetz et al.
NATURE REVIEWS GENETICS (2010)
DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS
Matthias Lauth et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons
Sigeng Chen et al.
PLOS ONE (2010)
Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer
Monique T. Barakat et al.
TRENDS IN MOLECULAR MEDICINE (2010)
High Levels of Id1 Expression Define B1 Type Adult Neural Stem Cells
Hyung-song Nam et al.
CELL STEM CELL (2009)
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6
Yuliya Zilberman et al.
JOURNAL OF CELL SCIENCE (2009)
Single Molecule Imaging Reveals Differences in Microtubule Track Selection Between Kinesin Motors
Dawen Cai et al.
PLOS BIOLOGY (2009)
Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines
Robert J. Lipinski et al.
BMC CELL BIOLOGY (2008)
Requirement of HDAC6 for transforming growth factor-β1-induced epithelial-mesenchymal transition
Bin Shan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
Yu Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
LARG and mDia1 link G alpha(12/13) to cell polarity and microtubule dynamics
Polyxeni Goulimari et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Beyond polymer polarity: how the cytoskeleton builds a polarized cell
Rong Li et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response
SoHee Kwon et al.
GENES & DEVELOPMENT (2007)
Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites
Maarten F. Bijlsma et al.
CELLULAR SIGNALLING (2007)
Patched1 regulates Hedgehog signaling at the primary cilium
Rajat Rohatgi et al.
SCIENCE (2007)
HEF1-Dependent aurora a activation induces disassembly of the primary cilium
Elena N. Pugacheva et al.
CELL (2007)
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
Jim P. Dompierre et al.
JOURNAL OF NEUROSCIENCE (2007)
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
Cyril Boyault et al.
GENES & DEVELOPMENT (2007)
Microtubule acetylation promotes kinesin-1 binding and transport
Nathan A. Reed et al.
CURRENT BIOLOGY (2006)
Mechanistic insight into how Shh patterns the vertebrate limb
Edwina McGlinn et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2006)
The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma
XB Deng et al.
CANCER RESEARCH (2006)
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase
CS Collins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
NErk/Dyrk1B - A multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival
Stephen E. Mercer et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2006)
Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis:: deactivation is induced by matrigel and N-acetylcysteine
R Jesnowski et al.
LABORATORY INVESTIGATION (2005)
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells
ER Gomes et al.
CELL (2005)
4-D single particle tracking of synthetic and proteinaceous microspheres reveals preferential movement of nuclear particles along chromatin-poor tracks
CP Bacher et al.
BMC CELL BIOLOGY (2004)
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Y Kawaguchi et al.
CELL (2003)
Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
S Etienne-Manneville et al.
NATURE (2003)
Post-translational modifications regulate microtubule function
S Westermann et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Small molecule modulation of Smoothened activity
JK Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
HDAC6 is a microtubule-associated deacetylase
C Hubbert et al.
NATURE (2002)
Glycogen synthase kinase-3,β is complexed with tau protein in brain microtubules
W Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)