期刊
CELL AND TISSUE RESEARCH
卷 375, 期 3, 页码 563-574出版社
SPRINGER
DOI: 10.1007/s00441-018-2961-4
关键词
Mesenchymal stem cells; Cell therapy; Exosomes; Liposomes; Diabetes mellitus
类别
资金
- Russian Science Foundation [14-25-00179]
- Russian Science Foundation [14-25-00179] Funding Source: Russian Science Foundation
Mesenchymal stem cell (MSC) therapy represents an alternative approach for tissue regeneration and inflammation control. In spite of a huge amount of preclinical data that has been accumulated on the therapeutic properties of MSCs, there are many conflicting results, possibly due to differences in the properties of MSCs obtained from different sources or underestimated mechanisms of MSC in vivo behavior. This review consolidates the in vivo effects of MSC therapy, discusses the fate of MSCs after intravascular andlocal delivery and proposes possible trends in MSC therapy.
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