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Michael Willem et al.
NATURE (2015)
Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States
Li-San Wang et al.
JAMA NEUROLOGY (2015)
Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein
Janice A. Maloney et al.
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The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation
Iryna Benilova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Investigation of an amyloid precursor protein protective mutation (A673T) in a North American case-control sample of late-onset Alzheimer's disease
Mikhil N. Bamne et al.
NEUROBIOLOGY OF AGING (2014)
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population
Mia Kero et al.
NEUROBIOLOGY OF AGING (2013)
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
A Noncompetitive BACE1 Inhibitor TAK-070 Ameliorates Aβ Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease
Hiroaki Fukumoto et al.
JOURNAL OF NEUROSCIENCE (2010)
Active γ-secretase is localized to detergent-resistant membranes in human brain
Ji-Yeun Hur et al.
FEBS JOURNAL (2008)
Phosphoinositides suppress γ-secretase in both the detergent-soluble and -insoluble states
Satoko Osawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Aβ 11-40/42 production without γ-secretase ε-site cleavage
Hideaki Kume et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Equimolar production of amyloid β-protein and amyloid precursor protein intracellular domain from β-carboxyl-terminal fragment by β-secretase
Nobuto Kakuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Nicastrin functions as a γ-secretase-substrate receptor
S Shah et al.
CELL (2005)
Spatial segregation of γ-secretase and substrates in distinct membrane domains
KS Vetrivel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Longer forms of amyloid β protein:: Implications for the mechanism of intramembrane cleavage by γ-secretase
Y Qi-Takahara et al.
JOURNAL OF NEUROSCIENCE (2005)
Development of Aβ terminal end-specific antibodies and sensitive ELISA for Aβ variant
Y Horikoshi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Truncated carboxyl-terminal fragments of β-amyloid precursor protein are processed to amyloid β-proteins 40 and 42
S Funamoto et al.
BIOCHEMISTRY (2004)
Association of γ-secretase with lipid rafts in post-golgi and endosome membranes
KS Vetrivel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
γ-secretase activity is present in rafts but is not cholesterol-dependent
S Wada et al.
BIOCHEMISTRY (2003)
Potential link between amyloid β-protein 42 and C-terminal fragment γ 49-99 of β-amyloid precursor protein
T Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Distinct intramembrane cleavage of the β-amyloid precursor protein family resembling γ-secretase-like cleavage of Notch
YJ Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)