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注意：仅列出部分参考文献，下载原文获取全部文献信息。The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
Simon D. Harding et al.
NUCLEIC ACIDS RESEARCH (2018)
Estrogen receptor beta modulates permeability transition in brain mitochondria
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2018)
Calcium and regulation of the mitochondrial permeability transition
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CELL CALCIUM (2018)
Assembly of the membrane domain of ATP synthase in human mitochondria
Jiuya He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane
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SCIENCE (2018)
Channel formation by F-ATP synthase and the permeability transition pore: an update
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CURRENT OPINION IN PHYSIOLOGY (2018)
Mechanisms of transcriptional regulation by p53
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CELL DEATH AND DIFFERENTIATION (2018)
The unique histidine in OSCP subunit of F-ATP synthase mediates inhibition of the permeability transition pore by acidic pH
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EMBO REPORTS (2018)
Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice
Esha Gauba et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion
Alexanne Cuillerier et al.
HUMAN MOLECULAR GENETICS (2017)
Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction
Insun Park et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2017)
Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase
Jiuya He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Atomic model for the dimeric FO region of mitochondrial ATP synthase
Hui Guo et al.
SCIENCE (2017)
Control of Mitochondrial Remodeling by the ATPase Inhibitory Factor 1 Unveils a Pro-survival Relay via OPA1
Danilo Faccenda et al.
CELL REPORTS (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Ca2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition
Valentina Giorgio et al.
EMBO REPORTS (2017)
ATP synthase from Escherichia coli: Mechanism of rotational catalysis, and inhibition with the ε subunit and phytopolyphenols
Mayumi Nakanishi-Matsui et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2016)
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization
Wen Yang et al.
CELL (2016)
Normalization of NAD+ Redox Balance as a Therapy for Heart Failure
Chi Fung Lee et al.
CIRCULATION (2016)
Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology
Alexander Hahn et al.
MOLECULAR CELL (2016)
mTOR signaling pathway is inhibited downstream of the cyclophilin D-mediated mitochondrial permeability transition in honokiol-triggered regulated necrosis
Wei Tian et al.
MOLECULAR MEDICINE REPORTS (2016)
Structure of the mitochondrial ATP synthase from Pichia angusta determined by electron cryo-microscopy
Kutti R. Vinothkumar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Rotary ATPases: A New Twist to an Ancient Machine
Werner Kuehlbrandt et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease
Simon J. Beck et al.
NATURE COMMUNICATIONS (2016)
Assembly of F1F0-ATP synthases
Thilo Ruehle et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking
Jennifer Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE: CHANNEL FORMATION BY F-ATP SYNTHASE, INTEGRATION IN SIGNAL TRANSDUCTION, AND ROLE IN PATHOPHYSIOLOGY
Paolo Bernardi et al.
PHYSIOLOGICAL REVIEWS (2015)
Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 Å resolution
Edgar Morales-Rios et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
Vinodkumar B. Pillai et al.
NATURE COMMUNICATIONS (2015)
Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM
Anna Zhou et al.
ELIFE (2015)
Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase
S. Maniam et al.
CELL DEATH AND DIFFERENTIATION (2015)
F-ATPase of Drosophila melanogaster Forms 53-Picosiemen (53-pS) Channels Responsible for Mitochondrial Ca2+-induced Ca2+ Release
Sophia von Stockum et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function
Jing Pan et al.
CANCER PREVENTION RESEARCH (2014)
Loss of LRPPRC causes ATP synthase deficiency
Arnaud Mourier et al.
HUMAN MOLECULAR GENETICS (2014)
The Oligomycin-Sensitivity Conferring Protein of Mitochondrial ATP Synthase: Emerging New Roles in Mitochondrial Pathophysiology
Manuela Antoniel et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane Does Not Involve the Peripheral Benzodiazepine Receptor ( Translocator Protein of 18 kDa ( TSPO))
Justina Sileikyte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition
Michela Carraro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
Kambiz N. Alavian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The ATP synthase: the understood, the uncertain and the unknown
John E. Walker
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Regulation of mitochondrial F(o)F(1)ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977 bp deletion of mitochondrial DNA
Yu-Ting Wu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F1F0-ATP synthase
Marie Bergeaud et al.
CELL CYCLE (2013)
Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure
Georgios Karamanlidis et al.
CELL METABOLISM (2013)
Mechanism of inhibition of mitochondrial ATP synthase by 17β-Estradiol
Antonio J. M. Moreno et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2013)
Dimers of mitochondrial ATP synthase form the permeability transition pore
Valentina Giorgio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria
Bertram Daum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cardiac mitochondrial matrix and respiratory complex protein phosphorylation
Raul Covian et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
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CELL (2012)
Is p53 the Long-Sought Molecular Trigger for Cyclophilin D-Regulated Mitochondrial Permeability Transition Pore Formation and Necrosis?
Jason Karch et al.
CIRCULATION RESEARCH (2012)
Multiple proteins with essential mitochondrial functions have glycosylated isoforms
Amanda R. Burnham-Marusich et al.
MITOCHONDRION (2012)
Oligomycin frames a common drug-binding site in the ATP synthase
Jindrich Symersky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Modular assembly of yeast mitochondrial ATP synthase
Malgorzata Rak et al.
EMBO JOURNAL (2011)
Knockdown of DAPIT (Diabetes-associated Protein in Insulin-sensitive Tissue) Results in Loss of ATP Synthase in Mitochondria
Shigenori Ohsakaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
Heng Du et al.
NEUROBIOLOGY OF AGING (2011)
Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c
Vendula Havlickova et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)
Cyclophilin D in mitochondrial pathophysiology
Valentina Giorgio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)
NMR Studies of an Immunomodulatory Benzodiazepine Binding to its Molecular Target on the Mitochondrial F1F0-ATPase
Andrew C. Stelzer et al.
BIOPOLYMERS (2010)
Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency
Kei Fujimoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cyclophilin D Modulates Mitochondrial F0F1-ATP Synthase by Interacting with the Lateral Stalk of the Complex
Valentina Giorgio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Torque generation and elastic power transmission in the rotary F0F1-ATPase
Wolfgang Junge et al.
NATURE (2009)
Genetic Variation in ATP5O Is Associated with Skeletal Muscle ATP50 mRNA Expression and Glucose Uptake in Young Twins
Tina Ronn et al.
PLOS ONE (2009)
The structure of the membrane extrinsic region of bovine ATP synthase
David M. Rees et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
Heng Du et al.
NATURE MEDICINE (2008)
Domain compliance and elastic power transmission in rotary FOFl-ATPase
Hendrik Sielaff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hsp90 Inhibition Decreases Mitochondrial Protein Turnover
Daciana H. Margineantu et al.
PLOS ONE (2007)
Identification of two proteins associated with mammalian ATP synthase
Bjoern Meyer et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria
Ruming Chen et al.
FEBS LETTERS (2007)
Honokiol induces a necrotic cell death through the mitochondrial permeability transition pore
Ling Li et al.
CANCER RESEARCH (2007)
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
Christopher P. Baines et al.
NATURE CELL BIOLOGY (2007)
Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets
R. Bergholdt et al.
GENES AND IMMUNITY (2007)
Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor
Joanne Cleary et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Properties of the permeability transition in VDAC1-/- mitochondria
Alexandra Krauskopf et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
Mechanistic basis for therapeutic targeting of the mitochondrial F1F0-ATPase
Kathryn M. Johnson et al.
ACS CHEMICAL BIOLOGY (2006)
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
AC Schinzel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Properties of the permeability transition pore in mitochondria devoid of cyclophilin D
E Basso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423
KM Johnson et al.
CHEMISTRY & BIOLOGY (2005)
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
CP Baines et al.
NATURE (2005)
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
T Nakagawa et al.
NATURE (2005)
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
JE Kokoszka et al.
NATURE (2004)
FRET reveals changes in the F1-stator stalk interaction during activity of F1F0-ATP synthase
PD Gavin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2003)
PISCES: a protein sequence culling server
GL Wang et al.
BIOINFORMATICS (2003)
Modulation at a distance of proton conductance through the Saccharomyces cerevisiae mitochondrial F1F0-ATP synthase by variants of the oligomycin sensitivity-conferring protein containing substitutions near the C-terminus
GM Boyle et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2000)
The oligomycin axis of mitochondrial ATP synthase: OSCP and the proton channel
RJ Devenish et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2000)
The second stalk of Escherichia coli ATP synthase
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2000)
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