相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de lange et al.
NATURE GENETICS (2017)
The proton-sensing G protein-coupled receptor T-cell deathassociated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction
Akiomi Nagasaka et al.
SCIENTIFIC REPORTS (2017)
Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk
Kara G. Lassen et al.
IMMUNITY (2016)
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Isabelle Cleynen et al.
LANCET (2016)
The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)
Kuo Yan et al.
MOLECULAR MEDICINE REPORTS (2016)
Regulating Rho GTPases and their regulators
Richard G. Hodge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases
Verena Katharina Raker et al.
FRONTIERS IN IMMUNOLOGY (2016)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Differential Effect of Genetic Burden on Disease Phenotypes in Crohn's Disease and Ulcerative Colitis: Analysis of a North American Cohort
Ashwin N. Ananthakrishnan et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2014)
Role of extracellular proton-sensing OGR1 in regulation of insulin secretion and pancreatic β-cell functions
Chihiro Mogi et al.
ENDOCRINE JOURNAL (2014)
Mouse Macrophages Completely Lacking Rho Subfamily GTPases (RhoA, RhoB, and RhoC) Have Severe Lamellipodial Retraction Defects, but Robust Chemotactic Navigation and Altered Motility
Volker Koenigs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia
Ye Jin et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Ionotropic and Metabotropic Proton-Sensing Receptors Involved in Airway Inflammation in Allergic Asthma
Haruka Aoki et al.
MEDIATORS OF INFLAMMATION (2014)
Suppression of p21Rac Signaling and Increased Innate Immunity Mediate Remission in Crohn's Disease
Kaushal Parikh et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway
James C. Lee et al.
CELL (2013)
Regulation of inflammation by extracellular acidification and proton-sensing GPCRs
Fumikazu Okajima
CELLULAR SIGNALLING (2013)
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH
H. Saxena et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
The Proton-activated G Protein Coupled Receptor OGR1 Acutely Regulates the Activity of Epithelial Proton Transport Proteins
Nilufar Mohebbi et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)
Activation of T cell death-associated gene 8 regulates the cytokine production of T cells and macrophages in vitro
Yoshiko Onozawa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA
Noah P. Zimmerman et al.
INFLAMMATORY BOWEL DISEASES (2012)
Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy
Michael Scharl et al.
INFLAMMATORY BOWEL DISEASES (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Activation of T cell death-associated gene 8 attenuates inflammation by negatively regulating the function of inflammatory cells
Yoshiko Onozawa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13
Tohru Kozasa et al.
JOURNAL OF BIOCHEMISTRY (2011)
Peritoneal changes due to laparoscopic surgery
W. J. A. Brokelman et al.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2011)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke et al.
NATURE GENETICS (2010)
The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor
Yuichiro Ihara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The preclinical pharmacology of roflumilast - A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease
Armin Hatzelmann et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2010)
Cohort Profile: The Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS)
Valerie Pittet et al.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2009)
Involvement of Proton-Sensing TDAG8 in Extracellular Acidification-Induced Inhibition of Proinflammatory Cytokine Production in Peritoneal Macrophages
Chihiro Mogi et al.
JOURNAL OF IMMUNOLOGY (2009)
Cyclic AMP - Master regulator of innate immune cell function
Carlos H. Serezani et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in raw 264.7 macrophages
Pil-hoon Park et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Genetic Mapping in Human Disease
David Altshuler et al.
SCIENCE (2008)
G12/G13-mediated signalling in mammalian physiology and disease
Thomas Worzfeld et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Microtubule dynamics and Rac-1 signaling independently regulate barrier function in lung epithelial cells
Magdalena J. Lorenowicz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Peritoneal acidosis mediates immunoprotection in laparoscopic surgery
Eric J. Hanly et al.
SURGERY (2007)
Extracellular acidosis triggers the maturation of human dendritic cells and the production of IL-12
Diego Martinez et al.
JOURNAL OF IMMUNOLOGY (2007)
GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
Xose R. Bustelo et al.
BIOESSAYS (2007)
Review - Receptors for protons or lipid messengers or both?
Klaus Seuwen et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2006)
Mammalian G proteins and their cell type specific functions
N Wettschureck et al.
PHYSIOLOGICAL REVIEWS (2005)
Identification of T cell death-associated gene 8 ( TDAG8) as a novel acid sensing G-protein-coupled receptor
S Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells
CG Radu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor
JQ Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Proton-sensing G-protein-coupled receptors
MG Ludwig et al.
NATURE (2003)
Receptor-dependent RhoA activation in G12/G13-deficient cells -: Genetic evidence for an involvement of Gq/G11
S Vogt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
N Sugimoto et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Rho GTPases in cell biology
S Etienne-Manneville et al.
NATURE (2002)
Identification of a molecular target of psychosine and its role in globoid cell formation
DS Im et al.
JOURNAL OF CELL BIOLOGY (2001)
分享论文
