期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 83, 期 3, 页码 498-501出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2018.1547107
关键词
mRNA processing; spice; ginger; gingerol; shogaol
类别
资金
- Public Foundation of Elizabeth Arnold-Fuji
- Yamazaki Spice Promotion Foundation
- JSPS Kakenhi [17K19232]
- Grants-in-Aid for Scientific Research [17K19232] Funding Source: KAKEN
Inhibition of mRNA processing, including splicing in the nucleus, is a potential anti-cancer candidate. To obtain mRNA processing inhibitors, we have screened for active constituents from spices. Ginger, clove, and cinnamon showed an inhibitory effect on mRNA processing in the nucleus. Two components in ginger, 6-gingerol and 6-shogaol, exhibited the inhibition of mRNA processing.
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