期刊
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
卷 1864, 期 6, 页码 819-826出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbalip.2018.10.001
关键词
Macrophages; Asthma; Free fatty acids; Eicosanoids; IL-33; linoleic acid
资金
- National Institutes of Health [HL113071]
Group V Phospholipase A(2) (Pla2g5) is a member of the PLA(2) family of lipid-generating enzymes. It is expressed in immune and non-immune cell types and is inducible during several pathologic conditions serving context-specific functions. In this review, we recapitulate the protective and detrimental functions of Pla2g5 investigated through preclinical and translational approaches. This article is part of a Special Issue entitled Novel functions of phospholipase A(2) Guest Editors: Makoto Murakami and Gerard Lambeau.
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