期刊
BEHAVIORAL NEUROSCIENCE
卷 132, 期 5, 页码 378-387出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/bne0000265
关键词
anterior thalamus; attention; nonspatial functions; stimulus preexposure effect; posterior cingulate cortex
资金
- Wellcome Trust [103722/Z/14/Z]
- BBSRC [BB/L021005/1]
- BBSRC [BB/L021005/1] Funding Source: UKRI
- Wellcome Trust [103722/Z/14/Z] Funding Source: Wellcome Trust
The present study examined the effects of excitotoxic lesions in 2 closely related structures, the anterior thalamic nuclei and the retrosplenial cortex, on latent inhibition. Latent inhibition occurs when nonreinforced preexposure to a stimulus retards the subsequent acquisition of conditioned responding to that stimulus. Latent inhibition was assessed in a within-subject procedure with auditory stimuli and food reinforcement. As expected, sham-operated animals were slower to acquire conditioned responding to a stimulus that had previously been experienced without consequence, relative to a non-preexposed stimulus. This latent inhibition effect was absent in rats with excitotoxic lesions in the anterior thalamic nuclei, as these animals conditioned to both stimuli at equivalent rates. The retrosplenial lesions appeared to spare latent inhibition, as these animals displayed a robust stimulus preexposure effect. The demonstration here that anterior thalamic nuclei lesions abolish latent inhibition is consistent with emerging evidence of the importance of these thalamic nuclei for attentional control.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据