期刊
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
卷 18, 期 6, 页码 769-775出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1871520617666170731115233
关键词
Plasma; cold atmospheric plasma; cancer cells; cancer treatment; reactive nitrogen species; reactive oxygen species
资金
- GW Institute of Nanotechnology
- National Science Foundation [1465061]
Background: Over the past five years, the cold atmospheric plasma-activated solutions (PAS) have shown their promissing application in cancer treatment. Similar as the common direct cold plasma treatment, PAS shows a selective anti-cancer capacity in vitro and in vivo. However, different from the direct cold atmospheric plasma (CAP) treatment, PAS can be stored for a long time and can be used without dependence on a CAP device. The research on PAS is gradually becoming a hot topic in plasma medicine. Objectives: In this review, we gave a concise but comprehensive summary on key topics about PAS including the development, current status, as well as the main conclusions about the anti-cancer mechanism achieved in past years. The approaches to make strong and stable PAS are also summarized.
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