期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 58, 期 7, 页码 2114-2119出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201810794
关键词
cycloaromatization; dual-gold catalysis; enediynes; isoindolinones
资金
- University of Wollongong
- Australian Research Council [DP180101332]
A synthesis of unconjugated (E)-enediynes from allenyl amino alcohols is reported and their gold-catalyzed cascade cycloaromatization to a broad range of enantioenriched substituted isoindolinones has been developed. Experimental and computational studies support the reaction proceeding via a dual-gold sigma,-activation mode, involving a key gold-vinylidene- and allenyl-gold-containing intermediate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据