期刊
AMERICAN JOURNAL OF SURGERY
卷 217, 期 4, 页码 677-681出版社
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjsurg.2018.07.009
关键词
Frailty; Sarcopenia; Morbidity; Colorectal cancer; Surgery
类别
Background: We aim to clarify if frailty affects severe postoperative complications in elective colorectal surgery. Methods: Consecutive 269 colorectal cancer patients older than 65 years undergoing curative surgery were enrolled in this study. The relevance of the frailty and sarcopenia to postoperative outcome was assessed. Clinical frailty (CF) was defined as clinical frailty scale (CFS) >= 4. Sarcopenia was assessed by measuring skeletal muscle area using computed tomography. Results: Seventy-eight patients (29%) had CF and 159 patients (59%) had sarcopenia. CF was significantly associated with older age (P = 0.0008), postoperative severe complications (P = 0.001), and postoperative in-hospital stay (P < 0.0001), although sarcopenia was not. Logistic regression analysis revealed that low anterior resection and CF were independent predictors of severe postoperative complications (P = 0.038 and P = 0.001, respectively). Conclusion: CF, but not sarcopenia, is a robust predictor of severe postoperative complications in patients with colorectal cancer. (C) 2018 Published by Elsevier Inc.
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