期刊
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
卷 98, 期 5, 页码 422-425出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PHM.0000000000001084
关键词
Charcot-Marie-Tooth Disease; Isokinetic Muscular Strength; Gait Parameters; Walking Speed
资金
- Clermont-Ferrand University Hospital
Charcot-Marie-Tooth disease type 1A is the most common hereditary neuropathy. Affected individuals have a distal motor deficit, initially affecting the lower limbs and impairing walking performance. Isokinetic dynamometry can be used to objectively assess muscle strength of patients with neuromuscular disorders. No studies have evaluated the effect of muscle strength deficits of knee extensors and flexors on walking parameters for patients with Charcot-Marie-Tooth disease type 1A. The purpose of this study was to determine correlations between the isokinetic muscular strength of knee flexors and knee extensors and walk parameters for patients with Charcot-Marie-Tooth disease type 1A. isokinetic muscular strength of the knee was assessed on an isokinetic dynamometer (Cybex) and walking by instrumented walkway analysis (GaitRite). We included 33 patients (23 females, mean +/- SDage 46.7 +/- 13.3 yrs, mean +/- SD body mass index 25.7 +/- 4.6 kg/m2). We found a correlation between walking speed and isokinetic muscular strength of knee extensors for the entire population and between walking speed and isokinetic muscular strength of knee extensors and knee flexors for patients younger than 50 yrs. Isokinetic dynamometry can provide objective measures of knee muscle strength, which is correlated with walking speed but not cadence or step/stride length of patients with Charcot-Marie-Tooth disease.
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