相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo
Mareike Lehmann et al.
EUROPEAN RESPIRATORY JOURNAL (2017)
The Clinical Potential of Senolytic Drugs
James L. Kirkland et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2017)
Idiopathic pulmonary fibrosis: Clinical behavior and aging associated comorbidities
Ivette Buendia-Roldan et al.
RESPIRATORY MEDICINE (2017)
Cellular senescence mediates fibrotic pulmonary disease
Marissa J. Schafer et al.
NATURE COMMUNICATIONS (2017)
Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2
Dauren Alimbetov et al.
BIOGERONTOLOGY (2016)
Profilin-PTEN interaction suppresses NF-κB activation via inhibition of IKK phosphorylation
Adeel H. Zaidi et al.
BIOCHEMICAL JOURNAL (2016)
Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts
Eun-Mi Noh et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN
Li Zhang et al.
JOURNAL OF IMMUNOLOGY (2015)
Loss of PTEN expression by mouse fibroblasts results in lung fibrosis through a CCN2-dependent mechanism
Sunil K. Parapuram et al.
MATRIX BIOLOGY (2015)
Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis
Shigehisa Yanagi et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation
Shin-El Cheng et al.
CLINICAL SCIENCE (2014)
PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a
Ni Zeng et al.
AGING CELL (2013)
Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity
Kahori Miyoshi et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury
Kazutetsu Aoshiba et al.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2013)
PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line
Seok-Ho Moon et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
Marco Chilosi et al.
TRANSLATIONAL RESEARCH (2013)
PTEN in cancer, metabolism, and aging
Ana Ortega-Molina et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
Epidemiology of idiopathic pulmonary fibrosis
Brett Ley et al.
Clinical Epidemiology (2013)
Predisposition for Disrepair in the Aged Lung
Viranuj Sueblinvong et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)
Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
Ana Ortega-Molina et al.
CELL METABOLISM (2012)
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Antero Salminen et al.
CELLULAR SIGNALLING (2012)
Blockade of the Nuclear Factor-κB Pathway in the Endothelium Prevents Insulin Resistance and Prolongs Life Spans
Yutaka Hasegawa et al.
CIRCULATION (2012)
NF-κB inhibition delays DNA damage-induced senescence and aging in mice
Jeremy S. Tilstra et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
Shunsuke Minagawa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
Idiopathic pulmonary fibrosis
Talmadge E. King et al.
LANCET (2011)
Activation of nuclear factor-kappa B signalling promotes cellular senescence
E. Rovillain et al.
ONCOGENE (2011)
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer
Imran Ahmad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis
Hong Xia et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Bleomycin and its Role in Inducing Apoptosis and Senescence in Lung Cells - Modulating Effects of Caveolin-1
Michael Kasper et al.
CURRENT CANCER DRUG TARGETS (2009)
Senescence-messaging secretome: SMS-ing cellular stress
Thomas Kuilman et al.
NATURE REVIEWS CANCER (2009)
The IκB kinase complex: master regulator of NF-κB signaling
Laura A. Solt et al.
IMMUNOLOGIC RESEARCH (2008)
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
Shigehisa Yanagi et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Direct evidence of endothelial oxidative stress with aging in humans -: Relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-κB
Anthony J. Donato et al.
CIRCULATION RESEARCH (2007)
Negative regulation of myofibroblast differentiation by PTEN (phosphatase and tensin homolog deleted on chromosome 10)
ES White et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)
Bleomycin induces cellular senescence in alveolar epithelial cells
K Aoshiba et al.
EUROPEAN RESPIRATORY JOURNAL (2003)