期刊
ADVANCED MATERIALS
卷 31, 期 45, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201804827
关键词
diagnosis; imaging; peptides; probes; targeted recognition
类别
资金
- National Natural Science Foundation of China [21775031, 31870992]
- Beijing Natural Science Foundation [L172035, 2172056]
- Beijing Talents Foundation [2015000021223ZK36]
- Key Research Program of the Chinese Academy of Sciences [KFZD-SW-210]
- Beijing Municipal Science and Technology Project [Z171100002017013]
A series of novel peptide-based molecular probes for different biomarkers is highlighted herein. These probes can provide targeted recognition with high affinity, high specificity, high penetration, and rapid excretion ability. These sensitive peptides can achieve rapid and specific detection when they are conjugated with imaging moieties or are formed into nanoprobes, which can be adapted for in vivo molecular imaging in targeted diagnosis and therapy.
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