期刊
ADVANCED MATERIALS
卷 31, 期 45, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201804785
关键词
cancer treatment; DNA-origami nanocarriers; drug delivery; self-assembly
类别
资金
- National Natural Science Foundation of China [31700871, 21573051, 21708004, 51761145044]
- Science Fund for Creative Research Groups of the National Natural Science Foundation of China [21721002]
- National Basic Research Program of China [2016YFA0201601, 2018YFA0208900]
- Beijing Municipal Science & Technology Commission [Z161100000116036]
- Key Research Program of Frontier Sciences, CAS [QYZDB-SSW-SLH029]
- CAS Interdisciplinary Innovation Team
- K. C. Wong Education Foundation
The recent decades have seen a surge of new nanomaterials designed for efficient drug delivery. DNA nanotechnology has been developed to construct sophisticated 3D nanostructures and artificial molecular devices that can be operated at the nanoscale, giving rise to a variety of programmable functions and fascinating applications. In particular, DNA-origami nanostructures feature rationally designed geometries and precise spatial addressability, as well as marked biocompatibility, thus providing a promising candidate for drug delivery. Here, the recent successful efforts to employ self-assembled DNA-origami nanostructures as drug-delivery vehicles are summarized. The remaining challenges and open opportunities are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据