期刊
SLAS TECHNOLOGY
卷 24, 期 1, 页码 70-78出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/2472630318799971
关键词
3D bioprinting; bioink; biomaterials; tissue engineering; tissue model
资金
- National Key Research and Development Program of China [2016YFB1101105]
- National Natural Science Foundation of China [31570996]
Tissue engineering has progressed tremendously over recent decades through the generation of functional tissue analogs. Traditional approaches based on seeding cells into scaffold are limited in their capacity to produce tissues with precise biomimetic properties. Three-dimensional (3D) bioprinting is one kind of fabrication technology used to precisely dispense cell-laden biomaterials for the construction of functional tissues or organs. In recent years, much research progress has been made in 3D bioprinting technology and its application in generating tissue analogs, including skin, heart valves, blood vessels, bone, and cardiac tissue. However, it still faces many technical challenges. In this review, we introduce the current progress in 3D bioprinting technology and focus on biomaterials and their potential applications in regenerative medicine and drug discovery. Current challenges are also discussed.
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