期刊
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
卷 2, 期 3, 页码 -出版社
ELSEVIER
DOI: 10.5936/csbj.201209008
关键词
directed evolution; rational design; semi-rational design; diversity generation; focused library; mutational effect
资金
- European Community's Seventh Framework Program EU-FP7 (OXYGREEN) [212281]
The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in this rapidly growing field. We will restrict ourselves to overview the availability, usability and limitations of web servers, databases and other computational tools proposed in the last five years. The goal of this review is to provide concise information about currently available computational resources to assist the design of directed evolution based protein engineering experiment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据