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Casein Kinase 1 Delta Regulates the Pace of the Mammalian Circadian Clock
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Casein Kinase I gamma 2 Down-Regulates Trafficking of Ceramide in the Synthesis of Sphingomyelin
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MOLECULAR BIOLOGY OF THE CELL (2009)
Oxidative stress and metabolic syndrome
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NATURE (2009)
Casein kinase I δ/ε phosphorylates topoisomerase II at serine-1106 and modulates DNA cleavage activity
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NUCLEIC ACIDS RESEARCH (2009)
CK1 modulates the transcriptional activity of ER via AIB1 in an estrogen-dependent manner and regulates ERAIB1 interactions (Publication with Expression of Concern. See vol. 49, pg. 3602, 2021)
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NUCLEIC ACIDS RESEARCH (2009)
Immunohistochemical Characterisation of Cell-Type Specific Expression of CK1δ in Various Tissues of Young Adult BALB/c Mice
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PLOS ONE (2009)
A Large Scale shRNA Barcode Screen Identifies the Circadian Clock Component ARNTL as Putative Regulator of the p53 Tumor Suppressor Pathway
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PLOS ONE (2009)
CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Inhibition of casein kinase I ε/δ produces phase shifts in the circadian rhythms of Cynomolgus monkeys
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PSYCHOPHARMACOLOGY (2009)
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SCIENCE SIGNALING (2009)
The flaviviral methyltransferase is a substrate of Casein Kinase 1
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VIRUS RESEARCH (2009)
Casein kinase 1α interacts with RIP1 and regulates NF-κB activation
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BIOCHEMISTRY (2008)
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Identification of novel protein kinase CK1 delta (CK1δ) inhibitors through structure-based virtual screening
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
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Phosphorylation of RhoB by CK1 impedes actin stress fiber organization and epidermal growth factor receptor stabilization
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JOURNAL OF MEDICINAL CHEMISTRY (2008)
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Georgios Giamas et al.
BIOCHEMICAL JOURNAL (2007)
Intracellular trafficking of a polymorphism in the COOH terminus of the α-subunit of the human epithelial sodium channel is modulated by casein kinase 1
Wusheng Yan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Scaffold proteins confer diverse regulatory properties to protein kinase cascades
Jason W. Locasale et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
Diane P. Hanger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
An inhibitor of casein kinase Iε induces phase delays in circadian rhythms under free-running and entrained conditions
Lori Badura et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Activation of 5′-AMP-activated kinase with diabetes drug metformin induces casein kinase Iε (CKIε)-dependent degradation of clock protein mPer2
Jee Hyun Um et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF
Tarik Regad et al.
NATURE CELL BIOLOGY (2007)
Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts
Sophie Dupre-Crochet et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Regulation of Alzheimer's disease amyloid-β formation by casein kinase I
Marc Flajolet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage
Naval P. Shanware et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry
Josef Wissing et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Disease-associated casein kinase I δ mutation may promote adenomatous polyps formation via a Wnt/β-catenin independent mechanism
I-Chun Tsai et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Hepatitis C virus NS5A is a direct substrate of casein kinase I-α, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors
Manuela Quintavalle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Dual alterations in casein kinase I-ε and GSK-3β modulate β-catenin stability in hyperproliferating colonic epithelia
Shahid Umar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
The Gli code: an information nexus regulating cell fate, stemness and cancer
Ariel Ruiz i Altaba et al.
TRENDS IN CELL BIOLOGY (2007)
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network
Kieran Harvey et al.
NATURE REVIEWS CANCER (2007)
Targeting the Hedgehog pathway in cancer
Lee L. Rubin et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Casein kinase 1 delta (CK1δ) interacts with the SNARE associated protein snapin
Sonja Wolff et al.
FEBS LETTERS (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Binding of p53 to the central domain of Mdm2 is regulated by phosphorylation
Roman Kulikov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop
Qun He et al.
GENES & DEVELOPMENT (2006)
Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
Roman V. Kondratov et al.
GENES & DEVELOPMENT (2006)
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
Carrie L. Partch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The circadian gene Per1 plays an important role in cell growth and DNA damage control in human cancer cells
S Gery et al.
MOLECULAR CELL (2006)
Negative regulation of LRP6 function by casein kinase I ε phosphorylation
W Swiatek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1
HS Yin et al.
BIOCHEMISTRY (2006)
Human sebaceous tumors harbor inactivating mutations in LEF1
H Takeda et al.
NATURE MEDICINE (2006)
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
DR Carrasco et al.
CANCER CELL (2006)
Casein kinase le down-regulates phospho-Akt via PTEN, following genotoxic stress-induced apoptosis in hematopoietic cells
A Okamura et al.
LIFE SCIENCES (2006)
CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling
MA Price
GENES & DEVELOPMENT (2006)
Evidence for the direct involvement of βTrCP in Gli3 protein processing
BW Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Casein kinase 1γ couples Wnt receptor activation to cytoplasmic signal transduction
G Davidson et al.
NATURE (2005)
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
X Zeng et al.
NATURE (2005)
Inhibition of casein kinase I delta alters mitotic spindle formation and induces apoptosis in trophoblast cells
M Stöter et al.
ONCOGENE (2005)
Growing roles for the mTOR pathway
DD Sarbassov et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth
Y Jenkins et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Phosphorylation by double-time/CKIε and CKIα targets Cubitus interruptus for slimb/β-TRCP-mediated proteolytic processing
JH Jia et al.
DEVELOPMENTAL CELL (2005)
Interaction of casein kinase 1 delta (CK1δ) with the light chain LC2 of microtubule associated protein 1A (MAP1A)
S Wolff et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)
Phosphorylation of FADD at serine 194 by CKIα regulates its nonapoptotic activities
EC Alappat et al.
MOLECULAR CELL (2005)
Regulation of p53-MDMX interaction by casein kinase 1 alpha
LH Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The casein kinase I family:: participation in multiple cellular processes in eukaryotes
U Knippschild et al.
CELLULAR SIGNALLING (2005)
Coupling of human circadian and cell cycles by the timeless protein
K Ünsal-Kaçmaz et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity
A Yamamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development
U Knippschild et al.
ONKOLOGIE (2005)
Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules
GB Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Involvement of casein kinase Iε in cytokine-induced granulocytic differentiation
A Okamura et al.
BLOOD (2004)
Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks
Y Pommier et al.
ONCOGENE (2004)
Association of CPI-17 with protein kinase C and casein kinase I
E Zemlickova et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Somatic mutations and altered expression of the candidate tumor suppressors CSNK1ε, DLG1, and EDD/hHYD in mammary ductal carcinoma
TJ Fuja et al.
CANCER RESEARCH (2004)
Protein kinase CK1δ phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover
M Winter et al.
BIOCHEMISTRY (2004)
Casein kinase 1α interacts with retinoid x receptor and interferes with agonist-induced apoptosis
Y Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Casein kinase Iε plays a functional role in the transforming growth factor-β signaling pathway
DS Waddell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
G Rena et al.
EMBO REPORTS (2004)
Regulation of the C-Abl and Bcr-Abl tyrosine kinases
O Hantschel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iε
S Kani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tissue repair and stem cell renewal in carcinogenesis
PA Beachy et al.
NATURE (2004)
Activation of C-kinase eta through its cholesterol-3-sulfate-dependent phosphorylation by casein kinase I in vitro
M Okano et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)
Manipulation of alternative splicing by a newly developed inhibitor of Clks
M Muraki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The Wnt signaling pathway in development and disease
CY Logan et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2004)
Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-γ2, an estrogen-responsive kinase
SK Mishra et al.
ONCOGENE (2004)
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1
H Okamura et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site
EC Alappat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A noncanonical sequence phosphorylated by casein kinase 1 in β-catenin may play a role in casein kinase 1 targeting of important signaling proteins
O Marin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells
AM Martelli et al.
LEUKEMIA (2003)
DNA damage checkpoint control in cells exposed to ionizing radiation
G Iliakis et al.
ONCOGENE (2003)
Polyhalogenobenzimidazoles: Synthesis and their inhibitory activity against casein kinases
M Andrzejewska et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2003)
Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence
A Takaoka et al.
NATURE (2003)
Downregulation of Cap43 gene by !von Hippel-Lindau tumor suppressor protein in human renal cancer cells
K Masuda et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Casein kinase I delta (CKIδ) is involved in lymphocyte physiology
T Maritzen et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2003)
ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation
EM Hammond et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Casein kinase 1 regulates connexin-43 gap junction assembly
CD Cooper et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phosphorylation and regulation of β-catenin by casein kinase Iε
C Sakanaka
JOURNAL OF BIOCHEMISTRY (2002)
Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic carcinoma
HF Frierson et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Centrosomal anchoring of the protein kinase CK1δ mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450
JE Sillibourne et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Loss of p53 and centrosome hyperamplification
P Tarapore et al.
ONCOGENE (2002)
Patched acts catalytically to suppress the activity of Smoothened
J Taipale et al.
NATURE (2002)
MIM, a potential metastasis suppressor gene in bladder cancer
YG Lee et al.
NEOPLASIA (2002)
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iε
EJ Eide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Identification of casein kinase Iα interacting protein partners
T Dubois et al.
FEBS LETTERS (2002)
Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila
S Yanagawa et al.
EMBO JOURNAL (2002)
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1
MA Price et al.
CELL (2002)
Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
CM Liu et al.
CELL (2002)
Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II
T Dubois et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Structural features underlying the multisite phosphorylation of the a domain of the NF-AT4 transcription factor by protein kinase CK1
O Marin et al.
BIOCHEMISTRY (2002)
Hypoxia links ATR and p53 through replication arrest
EM Hammond et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Posttranslational mechanisms regulate the mammalian circadian clock
C Lee et al.
CELL (2001)
Hedgehog signaling in animal development: paradigms and principles
PW Ingham et al.
GENES & DEVELOPMENT (2001)
Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1ε
B Rubinfeld et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Four casein kinase I isoforms are differentially partitioned between nucleus and cytoplasm
Z Fu et al.
EXPERIMENTAL CELL RESEARCH (2001)
Physiological regulation of ß-catenin stability by Tcf3 and CK1ε
E Lee et al.
JOURNAL OF CELL BIOLOGY (2001)
Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8
S Desagher et al.
MOLECULAR CELL (2001)
Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors
J Rutter et al.
SCIENCE (2001)
Phosphorylation regulates intracellular trafficking of β-secretase
J Walter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Catalytic activity of protein kinase CK1δ (casein kinase 1δ) is essential for its normal subcellular localization
DM Milne et al.
EXPERIMENTAL CELL RESEARCH (2001)
p53 down-regulates CHK1 through p21 and the retinoblastoma protein
V Gottifredi et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects
L Behrend et al.
ONCOGENE (2000)
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling
WG Liu et al.
NATURE GENETICS (2000)
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
N Denef et al.
CELL (2000)
The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Iα-like isoform
VV Faundez et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I ε
E Vielhaber et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative disease
C Schwab et al.
NEUROBIOLOGY OF AGING (2000)
Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B
Y Katagiri et al.
NATURE CELL BIOLOGY (2000)
Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane
Y Feng et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Crystal structure of a conformation-selective casein kinase-1 inhibitor
N Mashhoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Casein kinase I is anchored on axonemal doublet microtubules and regulates flagellar dynein phosphorylation and activity
PF Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain
K Yasojima et al.
BRAIN RESEARCH (2000)
Interaction of casein kinase 1 delta (CK1δ) with post-Golgi structures, microtubules and the spindle apparatus
L Behrend et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2000)
Identification of casein kinase I substrates by in vitro expression cloning screening
ZH Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase - Effect on Mdm2 binding
K Sakaguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
E Batlle et al.
NATURE CELL BIOLOGY (2000)
Constitutive phosphorylation of the Parkinson's disease associated α-synuclein
M Okochi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)