期刊
FRONTIERS IN ONCOLOGY
卷 3, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2013.00202
关键词
chemoprevention; therapy; natural compound; Dionaea
类别
资金
- European Union [215009]
- Foundation de Recherche Cancer et Sang
- Recherches Scientifiques Luxembourg association
- Haerz fir kriibskrank Kanner association
- Action Lions Vaincre le Cancer association
- National Research Foundation (NRF) - MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) [2012-0001184]
- Seoul National University Research - Research Settlement Fund for the new faculty of SNU
Chemoprevention uses natural or synthetic molecules without toxic effects to prevent and/or block emergence and development of diseases including cancer. Many of these natural molecules modulate mitogenic signals involved in cell survival, apoptosis, cell cycle regulation, angiogenesis, or on processes involved in the development of metastases occur naturally, especially in fruits and vegetables bur also in non-comestible plants. Carnivorous plants including theVenus flytrap (Dionaea muscipula Solander ex Ellis) are much less investigated, but appear to contain a wealth of potent bioactive secondary metabolites. Aim of this review is to give insight into molecular mechanisms triggered by compounds isolated from these interesting plants with either therapeutic or chemopreventive potential.
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