4.6 Review

The Role of Extracellular Vesicles in Cancer: Cargo, Function, and Therapeutic Implications

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Ovarian cancer-derived extracellular vesicles affect normal human fibroblast behavior

Ilaria Giusti et al.

CANCER BIOLOGY & THERAPY (2018)

Article Oncology

Exosome-Based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients

Elena Castellanos-Rizaldos et al.

CLINICAL CANCER RESEARCH (2018)

Article Biochemistry & Molecular Biology

Dimerization of sortilin regulates its trafficking to extracellular vesicles

Shinsuke Itoh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Chemistry, Multidisciplinary

Technical challenges of working with extracellular vesicles

Marcel I. Ramirez et al.

NANOSCALE (2018)

Article Biochemistry & Molecular Biology

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells

K. E. Richards et al.

ONCOGENE (2017)

Article Pharmacology & Pharmacy

Extracellular vesicles as a source for non-invasive biomarkers in bladder cancer progression

Zoraida Andreu et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

Article Oncology

Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancer progression

Lei Pan et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)

Article Biotechnology & Applied Microbiology

Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis

Nao Nishida-Aoki et al.

MOLECULAR THERAPY (2017)

Article Multidisciplinary Sciences

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Sushrut Kamerkar et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Nitrite-derived nitric oxide reduces hypoxia-inducible factor 1α-mediated extracellular vesicle production by endothelial cells

Nicholas Burnley-Hall et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2017)

Article Multidisciplinary Sciences

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

Pasquale Sansone et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

Matthew J. Shurtleff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells

Zhiyun Wei et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

Masaki Takasugi et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

Akira Yokoi et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

Yun Teng et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

Akiko Takahashi et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA

Andrea Nemeth et al.

SCIENTIFIC REPORTS (2017)

Article Multidisciplinary Sciences

REG3β modifies cell tumor function by impairing extracellular vesicle uptake

Laia Bonjoch et al.

SCIENTIFIC REPORTS (2017)

Article Cell Biology

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper

Bogdan Mateescu et al.

JOURNAL OF EXTRACELLULAR VESICLES (2017)

Article Biochemistry & Molecular Biology

Qualitative differences in T-cell activation by dendritic cell-derived extracellular vesicle subtypes

Mercedes Tkach et al.

EMBO JOURNAL (2017)

Article Biochemistry & Molecular Biology

Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes

Olga A. Kossinova et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2017)

Article Oncology

MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer

Valentina R. Minciacchi et al.

CANCER RESEARCH (2017)

Review Pharmacology & Pharmacy

Extracellular vesicles for drug delivery

Pieter Vader et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Biochemistry & Molecular Biology

Reversible HuR-microRNA binding controls extracellular export of miR-122 and augments stress response

Kamalika Mukherjee et al.

EMBO REPORTS (2016)

Review Biochemical Research Methods

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery

Muhammad Nawaz et al.

EXPERT REVIEW OF PROTEOMICS (2016)

Article Multidisciplinary Sciences

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

Joanna Kowal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Urology & Nephrology

PLK-1 Silencing in Bladder Cancer by siRNA Delivered With Exosomes

Kristin A. Greco et al.

UROLOGY (2016)

Article Multidisciplinary Sciences

Diverse human extracellular RNAs are widely detected in human plasma

Jane E. Freedman et al.

NATURE COMMUNICATIONS (2016)

Article Cell Biology

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

Andrew J. McKenzie et al.

CELL REPORTS (2016)

Article Cell Biology

miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer

Marie Stampe Ostenfeld et al.

JOURNAL OF EXTRACELLULAR VESICLES (2016)

Article Oncology

Plasma exosome microRNAs are indicative of breast cancer

Bethany N. Hannafon et al.

BREAST CANCER RESEARCH (2016)

Article Urology & Nephrology

Exosomal miR-1290 and miR-375 as Prognostic Markers in Castration-resistant Prostate Cancer

Xiaoyi Huang et al.

EUROPEAN UROLOGY (2015)

Article Biochemistry & Molecular Biology

Commitment of Annexin A2 in recruitment of microRNAs into extracellular vesicles

Keitaro Hagiwara et al.

FEBS LETTERS (2015)

Review Biochemistry & Molecular Biology

Mechanisms of RNA loading into exosomes

Teresa Janas et al.

FEBS LETTERS (2015)

Article Biochemistry & Molecular Biology

CD90+liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA

Alice Conigliaro et al.

MOLECULAR CANCER (2015)

Article Multidisciplinary Sciences

Tumour exosome integrins determine organotropic metastasis

Ayuko Hoshino et al.

NATURE (2015)

Article Multidisciplinary Sciences

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

Sonia A. Melo et al.

NATURE (2015)

Review Biology

Uridylation and adenylation of RNAs

Song JianBo et al.

SCIENCE CHINA-LIFE SCIENCES (2015)

Article Biology

KRAS-dependent sorting of miRNA to exosomes

Diana J. Cha et al.

Article Biochemistry & Molecular Biology

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes

J. P. Webber et al.

ONCOGENE (2015)

Article Biochemistry & Molecular Biology

Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells

Tae Hoon Lee et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Cell Biology

Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes

Ugur Gezer et al.

CELL BIOLOGY INTERNATIONAL (2014)

Letter Cell Biology

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

Caitlin Williams et al.

CELL RESEARCH (2014)

Article Biochemistry & Molecular Biology

Exosome Uptake through Clathrin-mediated Endocytosis and Macropinocytosis and Mediating miR-21 Delivery

Tian Tian et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Medicine, Research & Experimental

miR-200-containing extracellular vesicles promote breast cancer cell metastasis

Minh T. N. Le et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Biochemical Research Methods

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

Shailender Singh Kanwar et al.

LAB ON A CHIP (2014)

Review Urology & Nephrology

The emerging role of extracellular vesicles as biomarkers for urogenital cancers

Muhammad Nawaz et al.

NATURE REVIEWS UROLOGY (2014)

Article Cell Biology

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

Mario Leonardo Squadrito et al.

CELL REPORTS (2014)

Article Biotechnology & Applied Microbiology

Expression of Serum Exosomal MicroRNA-21 in Human Hepatocellular Carcinoma

Hongwei Wang et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Biochemistry & Molecular Biology

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

Nobuyoshi Kosaka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

Daniel Perez-Hernandez et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemical Research Methods

Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids

Bow J. Tauro et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

Article Biotechnology & Applied Microbiology

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth

Arda Mizrak et al.

MOLECULAR THERAPY (2013)

Article Biotechnology & Applied Microbiology

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

Shin-ichiro Ohno et al.

MOLECULAR THERAPY (2013)

Article Multidisciplinary Sciences

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Carolina Villarroya-Beltri et al.

NATURE COMMUNICATIONS (2013)

Article Cell Biology

How pure are your vesicles?

Jason Webber et al.

JOURNAL OF EXTRACELLULAR VESICLES (2013)

Letter Cell Biology

As we wait: coping with an imperfect nomenclature for extracellular vesicles

Stephen J. Gould et al.

JOURNAL OF EXTRACELLULAR VESICLES (2013)

Article Oncology

Hypoxic enhancement of exosome release by breast cancer cells

Hamish W. King et al.

BMC CANCER (2012)

Article Immunology

Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro

Annamaria Marton et al.

IMMUNOLOGY LETTERS (2012)

Article Medicine, Research & Experimental

Exosome removal as a therapeutic adjuvant in cancer

Annette M. Marleau et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

Importance of RNA isolation methods for analysis of exosomal RNA: Evaluation of different methods

Maria Eldh et al.

MOLECULAR IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Hector Peinado et al.

NATURE MEDICINE (2012)

Article Biochemistry & Molecular Biology

Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Jessica Wahlgren et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

Muller Fabbri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Medicine, Research & Experimental

miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles

Mehmet Fatih Bolukbasi et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2012)

Article Biotechnology & Applied Microbiology

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez-Erviti et al.

NATURE BIOTECHNOLOGY (2011)

Article Multidisciplinary Sciences

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

Leonora Balaj et al.

NATURE COMMUNICATIONS (2011)

Article Oncology

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

Jason Webber et al.

CANCER RESEARCH (2010)

Article Clinical Neurology

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

Michele Guescini et al.

JOURNAL OF NEURAL TRANSMISSION (2010)

Article Oncology

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

Guilherme Rabinowits et al.

CLINICAL LUNG CANCER (2009)

Article Multidisciplinary Sciences

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

Khalid Al-Nedawi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biotechnology & Applied Microbiology

Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer

Shengming Dai et al.

MOLECULAR THERAPY (2008)

Article Multidisciplinary Sciences

Ceramide triggers budding of exosome vesicles into multivesicular Endosomes

Katarina Trajkovic et al.

SCIENCE (2008)

Review Cell Biology

The emerging shape of the ESCRT machinery

Roger L. Williams et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Hematology

Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

AJ Abusamra et al.

BLOOD CELLS MOLECULES AND DISEASES (2005)

Article Medicine, Research & Experimental

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

MA Morse et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2005)

Article Biochemistry & Molecular Biology

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

J Wolfers et al.

NATURE MEDICINE (2001)