相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Epidermal growth factor receptor aptamer-conjugated polymer-lipid hybrid nanoparticles enhance salinomycin delivery to osteosarcoma and cancer stem cells
Zuochong Yu et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)
Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro
Alicja Urbaniak et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas
Ha Thi Vu et al.
CANCER SCIENCE (2018)
Salinomycin nanoparticles interfere with tumor cell growth and the tumor microenvironment in an orthotopic model of pancreatic cancer
Zahra Daman et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)
Biological activity of doubly modified salinomycin analogs - Evaluation in vitro and ex vivo
Michal Antoszczak et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Graphene Oxide-Silver Nanocomposite Enhances Cytotoxic and Apoptotic Potential of Salinomycin in Human Ovarian Cancer Stem Cells (OvCSCs): A Novel Approach for Cancer Therapy
Yun-Jung Choi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Promoted delivery of salinomycin sodium to lung cancer cells by dual targeting PLGA hybrid nanoparticles
Jie Zhou et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2018)
Nigericin Exerts Anticancer Effects on Human Colorectal Cancer Cells by Inhibiting Wnt/β-catenin Signaling Pathway
Fei Liu et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Targeted salinomycin delivery with EGFR and CD133 aptamers based dual-ligand lipid-polymer nanoparticles to both osteosarcoma cells and cancer stem cells
Fangyi Chen et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)
Chemical biology of salinomycin
Antoine Versini et al.
TETRAHEDRON (2018)
The enhanced delivery of salinomycin to CD133+ ovarian cancer stem cells through CD133 antibody conjugation with poly( lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles
Yi Mi et al.
ONCOLOGY LETTERS (2018)
A Novel Long Noncoding RNA (lncRNA), LL22NC03-N64E9.1, Promotes the Proliferation of Lung Cancer Cells and is a Potential Prognostic Molecular Biomarker for Lung Cancer
Hongyu Jing et al.
MEDICAL SCIENCE MONITOR (2018)
The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin
Xiaoli Huang et al.
ACS CENTRAL SCIENCE (2018)
Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+melanoma stem cells
Yi-bin Zeng et al.
ACTA PHARMACOLOGICA SINICA (2018)
Design and synthesis of conformationally constrained salinomycin derivatives
Wenxuan Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Synthesis and biological evaluation of salinomycin triazole analogues as anticancer agents
Minjian Huang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Zinc and its transporter ZIP6 are key mediators of breast cancer cell survival under high glucose conditions
Chihiro Matsui et al.
FEBS LETTERS (2017)
Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells
Kwang-Youn Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Polymer-lipid hybrid anti-HER2 nanoparticles for targeted salinomycin delivery to HER2-positive breast cancer stem cells and cancer cells
Jun Li et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)
Salinomycin's potential to eliminate glioblastoma stem cells and treat glioblastoma multiforme
Justin W. Magrath et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Anti-Tumor Effects of Cardiac Glycosides on Human Lung Cancer Cells and Lung Tumorspheres
Vivek Kaushik et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
Salinomycin reduces stemness and induces apoptosis on human ovarian cancer stem cell
Hyun-Gyo Lee et al.
JOURNAL OF GYNECOLOGIC ONCOLOGY (2017)
Autophagy inhibition enhances antiproliferative effect of salinomycin in pancreatic cancer cells
Sho Endo et al.
PANCREATOLOGY (2017)
A novel resveratrol-salinomycin combination sensitizes ER-positive breast cancer cells to apoptosis
Rajkumar Venkatadri et al.
PHARMACOLOGICAL REPORTS (2017)
Anti-tumorigenic effects of a novel digitoxin derivative on both estrogen receptor-positive and triple-negative breast cancer cells
Yogesh M. Kulkarni et al.
TUMOR BIOLOGY (2017)
Nigericin decreases the viability of multidrug-resistant cancer cells and lung tumorspheres and potentiates the effects of cardiac glycosides
Juan Sebastian Yakisich et al.
TUMOR BIOLOGY (2017)
Salinomycin: A new paradigm in cancer therapy
Jayant Dewangan et al.
TUMOR BIOLOGY (2017)
The combination therapy of salinomycin and gefitinib using poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles for targeting both lung cancer stem cells and cancer cells
Yu Zhang et al.
ONCOTARGETS AND THERAPY (2017)
Salinomycin repressed the epithelial-mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway
Rui Li et al.
ONCOTARGETS AND THERAPY (2017)
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma
Chiaki Tsuge Ishida et al.
ONCOTARGET (2017)
Improvement of dexamethasone sensitivity by chelation of intracellular Ca2+ in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation
Souleymane Abdoul-Azize et al.
ONCOTARGET (2017)
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer
Wei-Jun Wei et al.
THERANOSTICS (2017)
Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib
Juan Sebastian Yakisich et al.
STEM CELLS INTERNATIONAL (2017)
Codelivery of salinomycin and docetaxel using poly(D,L-lactic-co-glycolic acid)- poly(ethylene glycol) nanoparticles to target both gastric cancer cells and cancer stem cells
Lan Li et al.
ANTI-CANCER DRUGS (2017)
Salinomycin overcomes acquired tamoxifen resistance through AIB1 and inhibits cancer cell invasion in endocrine resistant breast cancer
Suwisit Manmuan et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2017)
Nigericin inhibits epithelial ovarian cancer metastasis by suppressing the cell cycle and epithelial-mesenchymal transition
Wen Wang et al.
BIOCHEMISTRY-MOSCOW (2017)
Salinomycin Induces Reactive Oxygen Species and Apoptosis in Aggressive Breast Cancer Cells as Mediated with Regulation of Autophagy
Kwang-Youn Kim et al.
ANTICANCER RESEARCH (2017)
Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC-3 cells
Kwang-Youn Kim et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Antitumor effects of naturally occurring cardiac glycosides convallatoxin and peruvoside on human ER plus and triple-negative breast cancers
Vivek Kaushik et al.
CELL DEATH DISCOVERY (2017)
Salinomycin encapsulated nanoparticles as a targeting vehicle for glioblastoma cells
R. Seda Tigli Aydin et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2016)
Autophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog
Yogesh M. Kulkarni et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity
Adam Hermawan et al.
ONCOLOGY REPORTS (2016)
Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway
Ying-Zi Fu et al.
ONCOLOGY REPORTS (2016)
Apoptotic effects of salinomycin on human ovarian cancer cell line (OVCAR-3)
Fuat Kaplan et al.
TUMOR BIOLOGY (2016)
Monensin Induces PC-3 Prostate Cancer Cell Apoptosis via ROS Production and Ca2+ Homeostasis Disruption
Sang-Hun Kim et al.
ANTICANCER RESEARCH (2016)
Salinomycin simultaneously induces apoptosis and autophagy through generation of reactive oxygen species in osteosarcoma U2OS cells
Sang-Hun Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
An iTEP-salinomycin nanoparticle that specifically and effectively inhibits metastases of 4T1 orthotopic breast tumors
Peng Zhao et al.
BIOMATERIALS (2016)
Salinomycin inhibits metastatic colorecta cancer growth and interferes with Wnt/β-catenin signaling in CD133+ human colorectal cancer cells
Johannes Klose et al.
BMC CANCER (2016)
CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel
Eameema Muntimadugu et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2016)
MCL-1 is the key target of adjuvant chemotherapy to reverse the cisplatin-resistance in NSCLC
Jun Ma et al.
GENE (2016)
Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance
Ahmed M. Hegazy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells
Chien-Lin Lu et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2016)
Copper transporters and chaperones CTR1, CTR2, ATOX1, and CCS as determinants of cisplatin sensitivity
Kristin M. Bompiani et al.
METALLOMICS (2016)
Codelivery of salinomycin and doxorubicin using nanoliposomes for targeting both liver cancer cells and cancer stem cells
Zhirong Gong et al.
NANOMEDICINE (2016)
Cancer stem cell drugs target K-ras signaling in a stemness context
A. K. Najumudeen et al.
ONCOGENE (2016)
Structure-activity & structure-toxicity relationship study of salinomycin diastereoisomers and their benzoylated derivatives
Wenxuan Zhang et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization
Vasileios A. Stamelos et al.
PLOS ONE (2016)
Salinomycin Hydroxamic Acids: Synthesis, Structure, and Biological Activity of Polyether Ionophore Hybrids
Bjorn Borgstrom et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells
Le Yu et al.
ONCOTARGET (2016)
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo
Szu-Jung Chen et al.
ONCOTARGET (2016)
Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma
Katharina Blatt et al.
ONCOTARGET (2016)
Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma
Enric Xipell et al.
Oncotarget (2016)
Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases
Ann-Katrin Sommer et al.
ONCOTARGET (2016)
Anticancer Activity of Polyether Ionophore-Salinomycin
Michal Antoszczak et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2015)
Salinomycin possesses anti-tumor activity and inhibits breast cancer stem-like cells via an apoptosis-independent pathway
Hyunsook An et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo
Rita Dornetshuber-Fleiss et al.
BIOCHEMICAL PHARMACOLOGY (2015)
Electrogenic and nonelectrogenic ion fluxes across lipid and mitochondrial membranes mediated by monensin and monensin ethyl ester
Yuri N. Antonenko et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Plasma membrane calcium channels in cancer: Alterations and consequences for cell proliferation and migration
Nadine Deliot et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling
Ying Lu et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2015)
Novel perspectives in cancer therapy: Targeting ion channels
Annarosa Arcangeli et al.
DRUG RESISTANCE UPDATES (2015)
ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
Li-sen Qin et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Salinomycin enhances doxorubicin-induced cytotoxicity in multidrug resistant MCF-7/MDR human breast cancer cells via decreased efflux of doxorubicin
Kwang-Youn Kim et al.
MOLECULAR MEDICINE REPORTS (2015)
Co-Eradication of Breast Cancer Cells and Cancer Stem Cells by Cross-Linked Multi lamellar Liposomes Enhances Tumor Treatment
Yu Jeong Kim et al.
MOLECULAR PHARMACEUTICS (2015)
iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells
Xiaoli Mao et al.
NANOMEDICINE (2015)
The promotion of salinomycin delivery to hepatocellular carcinoma cells through EGFR and CD133 aptamers conjugation by PLGA nanoparticles
Jianxin Jiang et al.
NANOMEDICINE (2015)
Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells
Chen Zhang et al.
ONCOLOGY REPORTS (2015)
Obatoclax induces Beclin 1-and ATG5-dependent apoptosis and autophagy in adenoid cystic carcinoma cells
L-Z Liang et al.
ORAL DISEASES (2015)
Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics
Elena G. Govorunova et al.
SCIENCE (2015)
Early effects of the antineoplastic agent salinomycin on mitochondrial function
A. Manago et al.
CELL DEATH & DISEASE (2015)
Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells
Youlin Deng et al.
SCIENTIFIC REPORTS (2015)
Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin
Sara Castiglioni et al.
SCIENTIFIC REPORTS (2015)
Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics
Maximilian Boesch et al.
STEM CELLS TRANSLATIONAL MEDICINE (2015)
Salinomycin inhibits the tumor growth of glioma stem cells by selectively suppressing glioma-initiating cells
Tunan Chen et al.
MOLECULAR MEDICINE REPORTS (2015)
Semisynthesis of SY-1 for Investigation of Breast Cancer Stem Cell Selectivity of C-Ring-Modified Salinomycin Analogues
Xiaoli Huang et al.
ACS CHEMICAL BIOLOGY (2014)
Salinomycin inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cell in vitro and suppresses tumor growth in vivo
Danxin Wu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
The effect of hyaluronic acid functionalized carbon nanotubes loaded with salinomycin on gastric cancer stem cells
Hong-juan Yao et al.
BIOMATERIALS (2014)
Combination of AZD2281 (Olaparib) and GX15-070 (Obatoclax) results in synergistic antitumor activities in preclinical models of pancreatic cancer
Shaohua Chen et al.
CANCER LETTERS (2014)
A Phase II, Multicenter, Open-Label Study of Obatoclax Mesylate in Patients With Previously Untreated Myelodysplastic Syndromes With Anemia or Thrombocytopenia
Martha L. Arellano et al.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2014)
A Combination of Curcumin with Either Gramicidin or Ouabain Selectively Kills Cells That Express the Multidrug Resistance-linked ABCG2 Transporter
Divya K. Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Salinomycin Suppresses LRP6 Expression and Inhibits Both Wnt/β-catenin and mTORC1 Signaling in Breast and Prostate Cancer Cells
Wenyan Lu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
Use of Proton Pump Inhibitors as Adjunct Treatment for Triple-Negative Breast Cancers. An Introductory Study
Wayne Goh et al.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2014)
Gramicidin A Blocks Tumor Growth and Angiogenesis through Inhibition of Hypoxia-Inducible Factor in Renal Cell Carcinoma
Justin M. David et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice
Lucie Tumova et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Randomized phase II study of carboplatin and etoposide with or without obatoclax mesylate in extensive-stage small cell lung cancer
Corey J. Langer et al.
LUNG CANCER (2014)
Inhibition of Autophagic Flux by Salinomycin Results in Anti-Cancer Effect in Hepatocellular Carcinoma Cells
Johannes Klose et al.
PLOS ONE (2014)
A Multicenter Phase I/II Study of Obatoclax Mesylate Administered as a 3-or 24-Hour Infusion in Older Patients with Previously Untreated Acute Myeloid Leukemia
Aaron D. Schimmer et al.
PLOS ONE (2014)
Ion channels and transporters in the development of drug resistance in cancer cells
Else K. Hoffmann et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Regulation of voltage-gated sodium channel expression in cancer: hormones, growth factors and auto-regulation
Scott P. Fraser et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
The mycotoxin beauvericin induces apoptotic cell death in H4IIE hepatoma cells accompanied by an inhibition of NF-κB-activity and modulation of MAP-kinases
Wim Waetjen et al.
TOXICOLOGY LETTERS (2014)
Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
J. Mao et al.
CELL DEATH & DISEASE (2014)
hERG channel function: beyond long QT
Joseph J. Babcock et al.
ACTA PHARMACOLOGICA SINICA (2013)
Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells
Tianliang Li et al.
AUTOPHAGY (2013)
Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance
Wen Yue et al.
AUTOPHAGY (2013)
Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia
Karen A. Urtishak et al.
BLOOD (2013)
Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy
Nichola Cruickshanks et al.
CANCER BIOLOGY & THERAPY (2013)
Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes
F. Basit et al.
CELL DEATH AND DIFFERENTIATION (2013)
BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
Eleni D. Lagadinou et al.
CELL STEM CELL (2013)
Targeting apoptosis by the remodelling of calcium-transporting proteins in cancerogenesis
Charlotte Dubois et al.
FEBS JOURNAL (2013)
Nigericin selectively targets cancer stem cells in nasopharyngeal carcinoma
Cheng-Cheng Deng et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Mechanism of action of salinomycin on growth and migration in pancreatic cancer cell lines
Lei He et al.
PANCREATOLOGY (2013)
βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer
Sandeep Singh et al.
PLOS ONE (2013)
PMA and Ionomycin Induce Glioblastoma Cell Death: Activation-Induced Cell-Death-Like Phenomena Occur in Glioma Cells
Sheng Han et al.
PLOS ONE (2013)
Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species
Jin Zhou et al.
TOXICOLOGY LETTERS (2013)
Structures and Properties of Naturally Occurring Polyether Antibiotics
Jacek Rutkowski et al.
BIOMED RESEARCH INTERNATIONAL (2013)
pH sensing and regulation in cancer
Mehdi Damaghi et al.
FRONTIERS IN PHYSIOLOGY (2013)
Polyether ionophores-promising bioactive molecules for cancer therapy
Adam Huczynski
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Antiproliferative activity of salinomycin and its derivatives
Adam Huczynski et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Experience with obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist in patients with relapsed or refractory classical Hodgkin lymphoma
Yasuhiro Oki et al.
BLOOD (2012)
A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation
Kuen-Feng Chen et al.
CANCER LETTERS (2012)
Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists
Jung-Chen Su et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells
Prajakta S. Oak et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Salinomycin as a Drug for Targeting Human Cancer Stem Cells
Cord Naujokat et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)
Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species
Berlinda Verdoodt et al.
PLOS ONE (2012)
Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo
Fan Wang et al.
PLOS ONE (2012)
Lapatinib and Obatoclax Kill Breast Cancer Cells through Reactive Oxygen Species-Dependent Endoplasmic Reticulum Stress
Nichola Cruickshanks et al.
MOLECULAR PHARMACOLOGY (2012)
Obatoclax and Lapatinib Interact to Induce Toxic Autophagy through NOXA
Yong Tang et al.
MOLECULAR PHARMACOLOGY (2012)
Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization
Kwang-Youn Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
Serena Pillozzi et al.
BLOOD (2011)
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas
Elizabeth A. Brem et al.
BRITISH JOURNAL OF HAEMATOLOGY (2011)
Salinomycin inhibits osteosarcoma by targeting its tumor stem cells
Qing-Lian Tang et al.
CANCER LETTERS (2011)
Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells
Guan-Nan Zhang et al.
CANCER LETTERS (2011)
Synthetic Prodiginine Obatoclax (GX15-070) and Related Analogues: Anion Binding, Transmembrane Transport, and Cytotoxicity Properties
Borja Diaz de Grenu et al.
CHEMISTRY-A EUROPEAN JOURNAL (2011)
Prognostic value of the copper transporters, CTR1 and CTR2, in patients with ovarian carcinoma receiving platinum-based chemotherapy
Yoo-Young Lee et al.
GYNECOLOGIC ONCOLOGY (2011)
A phase II study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in relapsed small cell lung cancer
Paul K. Paik et al.
LUNG CANCER (2011)
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
Desheng Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Salinomycin induces calpain and cytochrome c-mediated neuronal cell death
W. Boehmerle et al.
CELL DEATH & DISEASE (2011)
The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy
Yue Wei et al.
AUTOPHAGY (2010)
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor
Roberta Riccioni et al.
BLOOD CELLS MOLECULES AND DISEASES (2010)
Flickering calcium microdomains signal turning of migrating cells
Chaoliang Wei et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2010)
Inhibition of MCL-1 enhances Lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy
Aditi Pandya Martin et al.
CANCER BIOLOGY & THERAPY (2010)
Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells
Veronica Lopez et al.
EXPERIMENTAL CELL RESEARCH (2010)
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
Laura Bonapace et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Salinomycin in cancer: A new mission for an old agent
Cord Naujokat et al.
MOLECULAR MEDICINE REPORTS (2010)
Ion channels and the hallmarks of cancer
Natalia Prevarskaya et al.
TRENDS IN MOLECULAR MEDICINE (2010)
GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy
N. Heidari et al.
CELL DEATH & DISEASE (2010)
Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK
F. McCoy et al.
CELL DEATH & DISEASE (2010)
Intracellular zinc increase inhibits p53-/- pancreatic adenocarcinoma cell growth by ROS/AIF-mediated apoptosis
M. Donadelli et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia
Susan M. O'Brien et al.
BLOOD (2009)
Human mitochondrial Mrs2 protein promotes multidrug resistance in gastric cancer cells by regulating p27, cyclin D1 expression and cytochrome C release
Yu Chen et al.
CANCER BIOLOGY & THERAPY (2009)
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Piyush B. Gupta et al.
CELL (2009)
Copper Transport Systems are Involved in Multidrug Resistance and Drug Transport
Tatsuhiko Furukawa et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Ca2+ signalling checkpoints in cancer:: remodelling Ca2+ for cancer cell proliferation and survival
H. Llewelyn Roderick et al.
NATURE REVIEWS CANCER (2008)
A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells
Jiannong Li et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis
Lin Yang et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2008)
Impaired activity of volume-sensitive Cl- channel is involved in cisplatin resistance of cancer cells
Elbert L. Lee et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells
Rita Dornetshuber et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2007)
Selective cytotoxic activity of valinomycin against HT-29 human colon carcinoma cells via down-regulation of GRP78
IJ Ryoo et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)
Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells
S Thebault et al.
CANCER RESEARCH (2006)
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
RA Cardone et al.
NATURE REVIEWS CANCER (2005)
Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells
G Samimi et al.
CLINICAL CANCER RESEARCH (2004)
Roles of K+ channels in regulating tumour cell proliferation and apoptosis
ZG Wang
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Regulation of cell cycle progression by calcium/calmodulin-dependent pathways
CR Kahl et al.
ENDOCRINE REVIEWS (2003)
Regulation of cell death: The calcium-apoptosis link
S Orrenius et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
AK Larsen et al.
PHARMACOLOGY & THERAPEUTICS (2000)