期刊
CANCERS
卷 10, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/cancers10070238
关键词
micelles; hybrid polymeric and stimuli-responsive nanomicelles; cancer therapy
类别
资金
- REA research grant from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) [PITN-GA-2012-316549]
- Nanoscience and Nanotechnology Institute, Kafrelsheikh University, Egypt
Micelles as colloidal suspension have attracted considerable attention due to their potential use for both cancer diagnosis and therapy. These structures have proven their ability to deliver poorly water-soluble anticancer drugs, improve drug stability, and have good penetration and site-specificity, leading to enhance therapeutic efficacy. Micelles are composed of hydrophobic and hydrophilic components assembled into nanosized spherical, ellipsoid, cylindrical, or unilamellar structures. For their simple formation, they are widely studied, either by using opposite polymers attachment consisting of two or more block copolymers, or by using fatty acid molecules that can modify themselves in a rounded shape. Recently, hybrid and responsive stimuli nanomicelles are formed either by integration with metal nanoparticles such as silver, gold, iron oxide nanoparticles inside micelles or by a combination of lipids and polymers into single composite. Herein, through this special issue, an updated overview of micelles development and their application for cancer therapy will be discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据