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FASEB JOURNAL (2013)
ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer
W. Du et al.
ONCOGENE (2013)
ADAMTS5 A New Player in the Vascular Field
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AMERICAN JOURNAL OF PATHOLOGY (2012)
ADAMTS5 Functions as an Anti-Angiogenic and Anti-Tumorigenic Protein Independent of Its Proteoglycanase Activity
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AMERICAN JOURNAL OF PATHOLOGY (2012)
A premature stop codon in the ADAMTS2 gene is likely to be responsible for dermatosparaxis in Dorper sheep
H. Zhou et al.
ANIMAL GENETICS (2012)
Identification of a thrombin cleavage site and a short form of ADAMTS-18
Jianhui Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
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Linda Troeberg et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2012)
Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice
Simon F. De Meyer et al.
BLOOD (2012)
ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice
Chintan Gandhi et al.
BLOOD (2012)
Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis
Masanari Obika et al.
CANCER SCIENCE (2012)
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) cleaves Reelin in an isoform-dependent manner
Arisa Hisanaga et al.
FEBS LETTERS (2012)
Brevican: A key proteoglycan in the perisynaptic extracellular matrix of the brain
Renato Frischknecht et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Anti-angiogenic properties of ADAMTS-4 in vitro
Yi-Ping Hsu et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2012)
von Willebrand factor: at the crossroads of bleeding and thrombosis
Cecile V. Denis et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2012)
ADAMTS-12 Metalloprotease Is Necessary for Normal Inflammatory Response
Angela Moncada-Pazos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Rearranging Exosites in Noncatalytic Domains Can Redirect the Substrate Specificity of ADAMTS Proteases
Weiqiang Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis
Athanasios Didangelos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury
Ryoji Tauchi et al.
JOURNAL OF NEUROINFLAMMATION (2012)
ADAMTS13 promotes angiogenesis and modulates VEGF-induced angiogenesis
Manfai Lee et al.
MICROVASCULAR RESEARCH (2012)
ADAMTS-13 is produced by glial cells and upregulated after spinal cord injury
Ryoji Tauchi et al.
NEUROSCIENCE LETTERS (2012)
Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change
Shiaw-Wei Tyan et al.
PLOS ONE (2012)
The ADAMTS1 Protease Gene Is Required for Mammary Tumor Growth and Metastasis
Carmela Ricciardelli et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer Identifies Genes Commonly Affected by Epigenetic Alterations
Young-Ho Kim et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
Proteoglycan degradation by the ADAMTS family of proteinases
Heather Stanton et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Endothelial von Willebrand factor regulates angiogenesis
Richard D. Starke et al.
BLOOD (2011)
AHR, a novel acute hypoxia-response sequence, drives reporter gene expression under hypoxia in vitro and in vivo
Mehmet Zeynel Cilek et al.
CELL BIOLOGY INTERNATIONAL (2011)
Partially Redundant Functions of Adamts1 and Adamts4 in the Perinatal Development of the Renal Medulla
Derek Boerboom et al.
DEVELOPMENTAL DYNAMICS (2011)
The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis
Laura Wagstaff et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2011)
Pericellular Versican Regulates the Fibroblast-Myofibroblast Transition A ROLE FOR ADAMTS5 PROTEASE-MEDIATED PROTEOLYSIS
Noriko Hattori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Adamts5 Deletion Blocks Murine Dermal Repair through CD44-mediated Aggrecan Accumulation and Modulation of Transforming Growth Factor β1 (TGFβ1) Signaling
Jennifer Velasco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Proteolytic Cleavage of Versican and Involvement of ADAMTS-1 in VEGF-A/VPF-Induced Pathological Angiogenesis
Yineng Fu et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2011)
Identification of ADAMTS18 as a gene mutated in Knobloch syndrome
Mohammed A. Aldahmesh et al.
JOURNAL OF MEDICAL GENETICS (2011)
Emerging roles for ADAMTS5 during development and disease
Christopher Kintakas et al.
MATRIX BIOLOGY (2011)
Regulated Expression of ADAMTS-12 in Human Trophoblastic Cells: A Role for ADAMTS-12 in Epithelial Cell Invasion?
Alexander G. Beristain et al.
PLOS ONE (2011)
ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells
Bon-Hun Koo et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold
Lucie Maingot et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors
Helene Gustavsson et al.
BMC CANCER (2010)
PGF2α-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer
Margaret C. Keightley et al.
BMC CANCER (2010)
High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers
Chao Zhang et al.
CANCER GENETICS AND CYTOGENETICS (2010)
Androgen Regulates ADAMTS15 Gene Expression in Prostate Cancer Cells
Chidi N. Molokwu et al.
CANCER INVESTIGATION (2010)
ADAMTS1 Contributes to the Acquisition of an Endothelial-like Phenotype in Plastic Tumor Cells
Carmen Casal et al.
CANCER RESEARCH (2010)
Variable Inhibition of Thrombospondin 1 against Liver and Lung Metastases through Differential Activation of Metalloproteinase ADAMTS1
Yoon-Jin Lee et al.
CANCER RESEARCH (2010)
Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Paulisally Hau Yi Lo et al.
CANCER RESEARCH (2010)
ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity
J. Dubail et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation
Hiroyuki Enomoto et al.
DEVELOPMENT (2010)
Processing of the Matricellular Protein Hevin in Mouse Brain Is Dependent on ADAMTS4
Matt S. Weaver et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
ADAMTS proteases: key roles in atherosclerosis?
Rebecca C. Salter et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2010)
Lentiviral shRNA knock-down of ADAMTS-5 and-9 restores matrix deposition in 3D chondrocyte culture
Teresa C. Coughlan et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2010)
Mutational and Functional Analysis Reveals ADAMTS18 Metalloproteinase as a Novel Driver in Melanoma
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MOLECULAR CANCER RESEARCH (2010)
Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies
Christine B. Kern et al.
MATRIX BIOLOGY (2010)
High-resolution melting analysis of ADAMTS18 methylation levels in gastric, colorectal and pancreatic cancers
Zhi Li et al.
MEDICAL ONCOLOGY (2010)
Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis
M. El Hour et al.
ONCOGENE (2010)
Identifying the human aggrecanase
A. J. Fosang et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
A splice variant of ADAMTS13 is expressed in human hepatic stellate cells and cancerous tissues
Noam Shomron et al.
THROMBOSIS AND HAEMOSTASIS (2010)
ADAMTS15 metalloproteinase inhibits breast cancer cell migration
L. Wagstaff et al.
BREAST CANCER RESEARCH (2010)
Fibroblast Growth Factor 2 Is an Intrinsic Chondroprotective Agent That Suppresses ADAMTS-5 and Delays Cartilage Degradation in Murine Osteoarthritis
Shi-Lu Chia et al.
ARTHRITIS AND RHEUMATISM (2009)
ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancer
Helene Gustavsson et al.
BJU INTERNATIONAL (2009)
C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke
Zongdong Li et al.
BLOOD (2009)
Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer
Cristina G. Viloria et al.
CANCER RESEARCH (2009)
A Review of the ADAMTS Family, Pharmaceutical Targets of the Future
Micky D. Tortorella et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression
Daniel R. McCulloch et al.
DEVELOPMENTAL CELL (2009)
Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues
Daniel R. McCulloch et al.
GENE EXPRESSION PATTERNS (2009)
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
Xin Lu et al.
GENES & DEVELOPMENT (2009)
INCREASED mRNA EXPRESSION OF ADAMTS METALLOPROTEINASES IN METASTATIC FOCI OF HEAD AND NECK CANCER
Kadir Demircan et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2009)
Characterization of proADAMTS5 processing by proprotein convertases
Jean-Michel Longpre et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Proteolytic Processing Causes Extensive Heterogeneity of Tissue Matrilin Forms
Harald W. A. Ehlen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
ADAMTS1 Is a Unique Hypoxic Early Response Gene Expressed by Endothelial Cells
Omer F. Hatipoglu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms
Suneel S. Apte
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer
Angela Moncada-Pazos et al.
JOURNAL OF CELL SCIENCE (2009)
ADAMTS9 activation by interleukin 1β via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes
Kursat Oguz Yaykasli et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
ADAMTS-4 and-8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
Dick Wagsater et al.
ATHEROSCLEROSIS (2008)
The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor
Soheila Sharghi-Namini et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
J. Evan Sadler
BLOOD (2008)
Aberrant methylation of ADAMTS1 in non-small cell lung cancer
Jin Eun Choi et al.
CANCER GENETICS AND CYTOGENETICS (2008)
ADAMTS-1 Metalloproteinase Promotes Tumor Development through the Induction of a Stromal Reaction In vivo
Natacha Rocks et al.
CANCER RESEARCH (2008)
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
Michelle G. Hamel et al.
EXPERIMENTAL NEUROLOGY (2008)
Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma (Publication with Expression of Concern. See vol. 141, pg. 2368, 2017)
Hong Lok Lung et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
Y. Luan et al.
OSTEOARTHRITIS AND CARTILAGE (2008)
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
Lidia Mosyak et al.
PROTEIN SCIENCE (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
The secreted metalloprotease ADAMTS20 is required for melanoblast survival
Debra L. Silver et al.
PLOS GENETICS (2008)
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)
Huey-Sheng Shieh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ADAMTS-5: The story so far
Amanda J. Fosang et al.
EUROPEAN CELLS & MATERIALS (2008)
Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice
Mirna Z. Ilic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas
H. Jin et al.
ONCOGENE (2007)
The genomic landscapes of human breast and colorectal cancers
Laura D. Wood et al.
SCIENCE (2007)
Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
Satoko Naito et al.
PATHOLOGY INTERNATIONAL (2007)
Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
Manas K. Majumdar et al.
ARTHRITIS AND RHEUMATISM (2007)
The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
Maria Llamazares et al.
JOURNAL OF CELL SCIENCE (2007)
TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4
Gareth J. Wayne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Anti-angiogenic peptides identified in thrombospondin type I domains
Emmanouil D. Karagiannis et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Proteolytic activities of human ADAMTS-5 - Comparative studies with ADAMTS-4
Christi Gendron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide
Bon-Hun Koo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Abnormal dentin structure in two novel gene mutations [COL1A1, Arg134Cys] and [ADAMTS2, Trp795-to-ter] causing rare type I collagen disorders
P. J. De Coster et al.
ARCHIVES OF ORAL BIOLOGY (2007)
Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9
P. H. Y. Lo et al.
ONCOGENE (2007)
The role of von Willebrand factor in thrombus formation
Zaverio M. Ruggeri
THROMBOSIS RESEARCH (2007)
ADAMTS1 is regulated by interleukin-1 beta, not by hypoxia, in chondrosarcoma
Thomas Kalinski et al.
HUMAN PATHOLOGY (2007)
ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2
Nathan V. Lee et al.
EMBO JOURNAL (2006)
The consensus coding sequences of human breast and colorectal cancers
Tobias Sjoeblom et al.
SCIENCE (2006)
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling
Zhenhua Xu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
An alternative spliced transcript of ADAMTS4 is present in human synovium from OA patients
Shane D. Wainwright et al.
MATRIX BIOLOGY (2006)
Activation by IL-1 of bovine articular chondrocytes in culture within a 3D collagen-based scaffold.: An in vitro model to address the effect of compounds with therapeutic potential in osteoarthritis
D. Cortial et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
ADAMTS1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2
Antoni X. Torres-Collado et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
Kannan Thirunavukkarasu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
Chuan-ju Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Human endothelial cells synthesize and release ADAMTS-13
N. Turner et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2006)
Cell-surface processing of pro-ADAMTS9 by furin
BH Koo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours
JR Dunn et al.
BRITISH JOURNAL OF CANCER (2006)
Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura
F Banno et al.
BLOOD (2006)
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively
YJ Liu et al.
ONCOGENE (2006)
Identification of substrates of the extracellular protease ADAMTS1 by DIGE proteomic analysis
Francesc Canals et al.
PROTEOMICS (2006)
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5,-9,-16 and-18
WL Zeng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma
S Porter et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Matrix-degrading proteases ADAMTS4 and ADAMTS5 (disintegrins and metalloproteinases with thrombospondin motifs 4 and 5) are expressed in human glioblastomas
J Held-Feindt et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Platelet-derived VWF-cleaving metalloprotease ADAMTS-13
L Liu et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
A Colige et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1
NV Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice
DG Motto et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Human glioblastomas overexpress ADAMTS-5 that degrades brevican
M Nakada et al.
ACTA NEUROPATHOLOGICA (2005)
Localization of ADAMTS 13 to the stellate cells of human liver
M Uemura et al.
BLOOD (2005)
ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells
M Krampert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Binding of ADAMTS13 to von Willebrand factor
EM Majerus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ADAMTS13 is expressed in hepatic stellate cells
WH Zhou et al.
LABORATORY INVESTIGATION (2005)
Adamts9 is widely expressed during mouse embryo development
KA Jungers et al.
GENE EXPRESSION PATTERNS (2005)
The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFβ1 in prostate cells:: Relevance to the accumulation of versican
NA Cross et al.
PROSTATE (2005)
Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: Evidence for specific and redundant patterns during ovulation
JS Richards et al.
BIOLOGY OF REPRODUCTION (2005)
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo
CB Little et al.
ARTHRITIS AND RHEUMATISM (2005)
ADAMTS-9 is synergistically induced by interleukin-1β and tumor necrosis factor α in OUMS-27 chondrosarcoma cells and in human chondrocytes
K Demircan et al.
ARTHRITIS AND RHEUMATISM (2005)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
NATURE (2005)
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton et al.
NATURE (2005)
The ADAMTS metalloproteinases
S Porter et al.
BIOCHEMICAL JOURNAL (2005)
Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (aggrecanase-1) in the trans-Golgi network
P Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma
S Porter et al.
CLINICAL CANCER RESEARCH (2004)
Effects of transforming growth factor-β on aggrecanase production and proteoglycan degradation by human chondrocytes in vitro
N Moulharat et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Adamts-1 is essential for the development and function of the urogenital system
L Mittaz et al.
BIOLOGY OF REPRODUCTION (2004)
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1
G Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (type VIIC) and common polymorphisms in the ADAMTS2 gene
A Colige et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
METH-2 silencing and promoter hypermethylation in NSCLC
JR Dunn et al.
BRITISH JOURNAL OF CANCER (2004)
Identification of prodomain determinants involved in ADAMTS-1 biosynthesis
JM Longpré et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system
M Arai et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice
SS Glasson et al.
ARTHRITIS AND RHEUMATISM (2004)
The carboxyl-terminal half region of ADAMTS-1 suppresses both tumorigenicity and experimental tumor metastatic potential
K Kuno et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
LA Collins-Racie et al.
MATRIX BIOLOGY (2004)
Dynamic induction of ADAMTS1 gene in the early phase of acute myocardial infarction
K Nakamura et al.
JOURNAL OF BIOCHEMISTRY (2004)
Cleavage of the ADAMTS13 propeptide is not required for protease activity
EM Majerus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165
A Luque et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transforming growth factor-β induces secretion of activated ADAMTS-2 -: A procollagen IIIN-proteinase
WM Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19:: transcriptional regulation by TNFα
DJ Bevitt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2003)
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1
RPT Somerville et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Aggrecanases and cartilage matrix degradation
H Nagase et al.
ARTHRITIS RESEARCH & THERAPY (2003)
Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein
MA Pratta et al.
ARTHRITIS AND RHEUMATISM (2003)
ADAMTS-13 activity in patients with brain and prostate tumors is mildly reduced, but not correlated to stage of malignancy and metastasis
M Bohm et al.
THROMBOSIS RESEARCH (2003)
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13)
B Plaimauer et al.
BLOOD (2002)
Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites
CR Flannery et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Expression profiling of primary non-small cell lung cancer for target identification
J Heighway et al.
ONCOGENE (2002)
Expression of ADAMTS1 during murine development
SNM Thai et al.
MECHANISMS OF DEVELOPMENT (2002)
The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M - A time-course study using real-time quantitative reverse transcription-polymerase chain reaction
PJT Koshy et al.
ARTHRITIS AND RHEUMATISM (2002)
Deficiency of von Willebrand factor-cleaving protease activity in the plasma of malignant patients
BH Koo et al.
THROMBOSIS RESEARCH (2002)
Expression and regulation of aggrecanase in arthritis:: The role of TGF-β
Y Yamanishi et al.
JOURNAL OF IMMUNOLOGY (2002)
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains
S Cal et al.
GENE (2002)
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 null mutant mice develop renal lesions mimicking obstructive nephropathy
H Yokoyama et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2002)
Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
XL Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
GG Levy et al.
NATURE (2001)
Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family
K Fujikawa et al.
BLOOD (2001)
Partial amino acid sequence of purified von Willebrand factor-cleaving protease
HE Gerritsen et al.
BLOOD (2001)
The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation
MD Tortorella et al.
OSTEOARTHRITIS AND CARTILAGE (2001)
Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats
S Cal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)
M Kashiwagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4
JD Sandy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility
SW Li et al.
BIOCHEMICAL JOURNAL (2001)
Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)
G Hashimoto et al.
FEBS LETTERS (2001)
ADAMTS9, a novel member of the ADAM-TS/metallospondin gene family
ME Clark et al.
GENOMICS (2000)
Mechanisms involved in cartilage proteoglycan catabolism
B Caterson et al.
MATRIX BIOLOGY (2000)
Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member
RT Matthews et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)
MD Tortorella et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Gene expression profiling in an in vitro model of angiogenesis
J Kahn et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function
T Shindo et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)