相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
J. Chen et al.
BRITISH JOURNAL OF CANCER (2010)
Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors
Julian Carretero et al.
CANCER CELL (2010)
Fructose Induces Transketolase Flux to Promote Pancreatic Cancer Growth
Haibo Liu et al.
CANCER RESEARCH (2010)
PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development
Reginald Hill et al.
CANCER RESEARCH (2010)
Glutaminolysis Supplying carbon or nitrogen or both for cancer cells?
Chi V. Dang
CELL CYCLE (2010)
LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest
Jennifer P. Morton et al.
GASTROENTEROLOGY (2010)
Radiosensitization and Stromal Imaging Response Correlates for the HIF-1 Inhibitor PX-478 Given with or without Chemotherapy in Pancreatic Cancer
David L. Schwartz et al.
MOLECULAR CANCER THERAPEUTICS (2010)
MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells
Jakub Godlewski et al.
MOLECULAR CELL (2010)
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
R. J. DeBerardinis et al.
ONCOGENE (2010)
Metformin Disrupts Crosstalk between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth
Krisztina Kisfalvi et al.
CANCER RESEARCH (2009)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
Selective Killing of Hypoxia-Inducible Factor-1-Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer
Shinae Kizaka-Kondoh et al.
CLINICAL CANCER RESEARCH (2009)
Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
Jose Miguel Lopez-Novoa et al.
EMBO MOLECULAR MEDICINE (2009)
Antidiabetic Therapies Affect Risk of Pancreatic Cancer
Donghui Li et al.
GASTROENTEROLOGY (2009)
Tumor suppressors and cell metabolism: a recipe for cancer growth
Russell G. Jones et al.
GENES & DEVELOPMENT (2009)
Role of Hypoxia in the Hallmarks of Human Cancer
Kai Ruan et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Ping Gao et al.
NATURE (2009)
Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect
Yijun Chen et al.
PLOS ONE (2009)
Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
Jihye Yun et al.
SCIENCE (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma
Mert M. Erkan et al.
NEOPLASIA (2009)
Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma
Carolin Reiser-Erkan et al.
CANCER BIOLOGY & THERAPY (2008)
Tumor cell metabolism: Cancer's Achilles' heel
Guido Kroemer et al.
CANCER CELL (2008)
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells
Stefania Cannito et al.
CARCINOGENESIS (2008)
Pancreatic Lkb1 deletion leads to acinar polarity defects and cystic neoplasms
Aram F. Hezel et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Direct regulation of TWIST by HIF-1α promotes metastasis
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2008)
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
David R. Wise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Role of Wnt/β-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1α
Yong-Guang Jiang et al.
INTERNATIONAL JOURNAL OF UROLOGY (2007)
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
Aristidis Moustakas et al.
CANCER SCIENCE (2007)
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
D. Grahame Hardie
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Effects of hypoxia on tumor metabolism
Jung-whan Kim et al.
CANCER AND METASTASIS REVIEWS (2007)
Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
Mert Erkan et al.
GASTROENTEROLOGY (2007)
Hypoxia upregulates amino acid transport in a human neuroblastoma cell line
Hideki Soh et al.
JOURNAL OF PEDIATRIC SURGERY (2007)
Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells
Weiwei Zhang et al.
CANCER BIOLOGY & THERAPY (2007)
Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves, glucose homeostasis, and decreases TRB3
Ho-Jin Koh et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Genetics and biology of pancreatic ductal adenocarcinoma
Aram F. Hezel et al.
GENES & DEVELOPMENT (2006)
Peutz-Jeghers syndrome and management recommendations
FM Giardiello et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw et al.
SCIENCE (2005)
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
MG Bachem et al.
GASTROENTEROLOGY (2005)
Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway
SD Bao et al.
CANCER CELL (2004)
Desmoplastic reaction in pancreatic cancer - Role of pancreatic stellate cells
MV Apte et al.
PANCREAS (2004)
Cancer genes and the pathways they control
B Vogelstein et al.
NATURE MEDICINE (2004)
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
N Bardeesy et al.
NATURE (2002)
Pancreatic tumors show high levels of hypoxia
AC Koong et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)