C-glycosylflavones from the leaves of Iris tectorum Maxim

A new C-glycosylflavone, 5-hydroxy1-4',7-dimethoxyflavone-6-C-[O-(alpha-L-3'-acetylrhamnopyranosyl)-1 -> 2-beta-D-glucopyranoside] (1), along with five known C-glycosylflavones, 5-hydroxy-4',7-dimethoxyflavone-6-C-[O-(alpha-L-2'-acetylrhamnopyranosyl)-1 -> 2-beta-D-glucopyranoside] (2), embinin (3), embigenin (4), swertisin (5) and swertiajaponin (6) were isolated from the leaves of Iris tectorum Maxim. Their structures were elucidated on the basis of extensive NMR experiments and spectral methods and their cytotoxic activities against A549 (lung cancer) human cell lines were determined. (C) 2012 Institute of Materia Medica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association. Production and hosting by Elsevier B.V. All rights reserved.