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uMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application
Zachary Dwight et al.
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Kevin A. Heyries et al.
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Jesus Gonzalez-Bosquet et al.
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Thomas Mikeska et al.
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John W. Pepper et al.
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Hao-Bing Liu et al.
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Kenji Osafune et al.
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F Diehl et al.
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E Kussell et al.
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HC Ma et al.
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