期刊
INFECTION AND DRUG RESISTANCE
卷 11, 期 -, 页码 1145-1155出版社
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S148664
关键词
zoonosis; epidemiology; diagnosis; treatment; molecular; functional studies
资金
- BKP grant, University of Malaya [BK013-2016, BK005-2017]
- Fogarty International Center at the National Institutes of Health under the Global Health Equity Scholars Consortium at Yale University [D43TW010540]
- Office of AIDS Research at the National Institutes of Health under the Global Health Equity Scholars Consortium at Yale University [D43TW010540]
- FOGARTY INTERNATIONAL CENTER [D43TW010540] Funding Source: NIH RePORTER
Originally known to cause simian malaria, Plasmodium knowlesi is now known as the fifth human malaria species. Since the publishing of a report that largely focused on human knowlesi cases in Sarawak in 2004, many more human cases have been reported in nearly all of the countries in Southeast Asia and in travelers returning from these countries. The zoonotic nature of this infection hinders malaria elimination efforts. In order to grasp the current perspective of knowlesi malaria, this literature review explores the different aspects of the disease including risk factors, diagnosis, treatment, and molecular and functional studies. Current studies do not provide sufficient data for an effective control program. Therefore, future direction for knowlesi research is highlighted here with a final aim of controlling, if not eliminating, the parasite.
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