Review of the biocompatibility of micro-arc oxidation coated titanium alloys

Titanium and its alloys are expected to be ideal materials for biomedical applications. Various approaches have been used for biological properties improvement Among various surface modification techniques, micro-arc oxidation (MAO), which can produce porous, adhesive and bioactive coatings for implantation, has aroused considerable attention. This paper gives a brief overview of biological assessment of bioactive coatings. It focuses mainly on the strategies of improving biological properties of MAO coated titanium and its alloys. The influence of the electrolyte, process parameters, pretreatment and post-treatment on the coating characteristics (surface micrograph, adhesion strength and biological compatibility etc.) is detailed in this article. MAO assisted by other methods to achieve superior biocompatibility is also discussed. Finally, the trend of development in the future is forecasted. (C) 2015 Elsevier Ltd. All rights reserved