4.1 Article

Community-associated methicillin-resistant staphylococcus aureus epidemic clone USA100; more than a nosocomial pathogen

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SPRINGERPLUS
卷 2, 期 -, 页码 -

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SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1186/2193-1801-2-133

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Staphylococcus; PFGE; Spa; MRSA; USA100

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  1. U.S. Army Research, Development and Engineering Command [W911SR-07-C-0084]

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Background: We characterized 100 USA100 epidemic MRSA from individuals in the community with no known healthcare-associated risk factors. Findings: Molecular epidemiology demonstrated 21 pulsed-field types and six spa types. SCCmec typing demonstrated that all of the strains possess the type II cassette. The staphylococcal enterotoxin D virulence gene was also present. Conclusion: Characterization of USA100 MRSA in the community illustrated the importance of nasal carriage, and the genetic diversity of the USA100 clone.

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