期刊
ORVOSI HETILAP
卷 154, 期 3, 页码 83-92出版社
AKADEMIAI KIADO ZRT
DOI: 10.1556/OH.2013.29530
关键词
statin; intolerance; myopathy; hepatopathy; cytochrom P450
Statin-induced adverse effects - facts and genes Statin therapy is considered to be safe and rarely associated with serious adverse events. However, a significant proportion of patients on statin therapy show some degree of intolerance which can lead to decreased adherence to statin therapy. The authors summarize the symptoms, signs and frequencies of the most common statin-induced adverse effects and their most important risk factors including some single nucleotide polymorphisms and gene mutations. Also, they review the available approaches to detect and manage the statin-intolerant patients. Orv. Hetil., 2013, 154, 83-92.
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