期刊
CENTRAL EUROPEAN JOURNAL OF PHYSICS
卷 10, 期 3, 页码 560-567出版社
SCIENDO
DOI: 10.2478/s11534-012-0016-0
关键词
polymer molecules; transport dynamics of biomolecules; noise in biological systems; Monte Carlo simulations
资金
- Ministero dell'Istruzione, dell'Universita e della Ricerca of Italian Government
Polymer translocation through the nanochannel is studied by means of a Monte Carlo approach, in the presence of a static or oscillating external electric voltage. The polymer is described as a chain molecule according to the two-dimensional bond fluctuation model. It moves through a piecewise linear channel, which mimics a nanopore in a biological membrane. The monomers of the chain interact with the walls of the channel, modelled as a reflecting barrier. We analyze the polymer dynamics, concentrating on the translocation time through the channel, when an external electric field is applied. By introducing a source of coloured noise, we analyze the effect of correlated random fluctuations on the polymer translocation dynamics.
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