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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
D. Tang et al.
ONCOGENE (2010)
Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation
Braedon McDonald et al.
SCIENCE (2010)
Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
Mark P. Chao et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis
Vilma Urbonaviciute et al.
AUTOIMMUNITY (2009)
Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development
Maria A. Mellen et al.
AUTOPHAGY (2009)
Chemotherapy induces ATP release from tumor cells
Isabelle Martins et al.
CELL CYCLE (2009)
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
J. Thorburn et al.
CELL DEATH AND DIFFERENTIATION (2009)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2009)
Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity
Marianela Candolfi et al.
CLINICAL CANCER RESEARCH (2009)
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
Theocharis Panaretakis et al.
EMBO JOURNAL (2009)
Radiation induces an antitumour immune response to mouse melanoma
Carmen A. Perez et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2009)
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
Michael R. Elliott et al.
NATURE (2009)
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Luigi Franchi et al.
NATURE IMMUNOLOGY (2009)
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors
Francois Ghiringhelli et al.
NATURE MEDICINE (2009)
Mitochondrial membrane permeabilization in neuronal injury
Lorenzo Galluzzi et al.
NATURE REVIEWS NEUROSCIENCE (2009)
Cardiac Glycosides Induce Cell Death in Human Cells by Inhibiting General Protein Synthesis
Andrea Perne et al.
PLOS ONE (2009)
Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators
Hiromi Imamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Shankar S. Iyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Immunogenicity of 56°C and UVC-Treated Prostate Cancer Is Associated With Release of HSP70 and HMGBI From Necrotic Cells
Davide Brusa et al.
PROSTATE (2009)
HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression
James F. Curtin et al.
PLOS MEDICINE (2009)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Daniel J. Klionsky et al.
AUTOPHAGY (2008)
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone
Jens Hoffmann et al.
CANCER RESEARCH (2008)
Chemotherapy Induces Tumor Clearance Independent of Apoptosis
Jennifer L. Guerriero et al.
CANCER RESEARCH (2008)
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
M. A. Mellen et al.
CELL DEATH AND DIFFERENTIATION (2008)
Immunogenic cancer cell death: a key-lock paradigm
Antoine Tesniere et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Targeting tumors with LIGHT to generate metastasis-clearing immunity
Ping Yu et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2008)
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
Hirotaka Kazama et al.
IMMUNITY (2008)
Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages
Virginia L. Vega et al.
JOURNAL OF IMMUNOLOGY (2008)
Apoptosis: controlled demolition at the cellular level
Rebecca C. Taylor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death
N. Tajeddine et al.
ONCOGENE (2008)
The endoplasmic reticulum stress response in immunity and autoimmunity
Derrick J. Todd et al.
NATURE REVIEWS IMMUNOLOGY (2008)
From regulation of dying cell engulfment to development of anti-cancer therapy
D. V. Krysko et al.
CELL DEATH AND DIFFERENTIATION (2008)
High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity
Marco E. Bianchi et al.
IMMUNOLOGICAL REVIEWS (2007)
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
Lionel Apetoh et al.
IMMUNOLOGICAL REVIEWS (2007)
The role of brain-derived neurotrophic factor (BDNF)- induced XBP1 splicing during brain development
Akiko Hayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Structure-function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA
A-L Pauleau et al.
ONCOGENE (2007)
Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox
Anna Rubartelli et al.
TRENDS IN IMMUNOLOGY (2007)
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Lionel Apetoh et al.
NATURE MEDICINE (2007)
High mobility group box I (HMGB1) release from tumor cells after treatment: Implications for development of targeted chemoimmunotherapy
Xiang Da (Eric) Dong et al.
JOURNAL OF IMMUNOTHERAPY (2007)
Cell death modalities: classification and pathophysiological implications
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2007)
Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
Radek Spisek et al.
BLOOD (2007)
Immune-cell lineage commitment: Translation from mice to humans
Kimberly J. Payne et al.
IMMUNITY (2007)
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis
Lorenzo Galluzzi et al.
APOPTOSIS (2007)
Bak and Bax are non-redundant during infection- and DNA damage-induced apoptosis
Oliver Kepp et al.
EMBO JOURNAL (2007)
Calreticulin exposure dictates the immunogenicity of cancer cell death
Michel Obeid et al.
NATURE MEDICINE (2007)
Leveraging the immune system during chemotherapy: Moving calreticulin to the cell surface converts apoptotic death from Silent to immunogenic
Michel Obeid et al.
CANCER RESEARCH (2007)
Mitochondrial membrane permeabilization in cell death
Guido Kroemer et al.
PHYSIOLOGICAL REVIEWS (2007)
Liaisons dangereuses: P2X(7) and the inflammasome
Francesco Di Virgilio
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Clearance of apoptotic and necrotic cells and its immunological consequences
Dmitri V. Krysko et al.
APOPTOSIS (2006)
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
Jerom Galon et al.
SCIENCE (2006)
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
Man Yu et al.
SHOCK (2006)
Hyaluronan fragments act as an endogenous danger signal by engaging TLR2
Kara A. Scheibner et al.
JOURNAL OF IMMUNOLOGY (2006)
Apoptotic cell removal in development and tissue homeostasis
Peter M. Henson et al.
TRENDS IN IMMUNOLOGY (2006)
Gout-associated uric acid crystals activate the NALP3 inflammasome
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NATURE (2006)
High mobility group box 1 protein interacts with multiple Toll-like receptors
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Interleukin-1 stimulates β-cell necrosis and release of the immunological adjuvant HMGB1
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PLOS MEDICINE (2006)
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Autophagy in cell death: an innocent convict?
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JOURNAL OF CLINICAL INVESTIGATION (2005)
High-mobility group box 1 protein (HMGB): Nuclear weapon in the immune arsenal
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NATURE REVIEWS IMMUNOLOGY (2005)
The cornified envelope: A model of cell death in the skin
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Select forms of tumor cell apoptosis induce dendritic cell maturation
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JOURNAL OF LEUKOCYTE BIOLOGY (2005)
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
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SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2005)
Hyaluronan fragments stimulate endothelial recognition of injury through TLR4
KR Taylor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
HMGB1 is an endogenous immune adjuvant released by necrotic cells
P Rovere-Querini et al.
EMBO REPORTS (2004)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)
Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture
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DNA SEQUENCE (2002)
The danger model: A renewed sense of self
P Matzinger
SCIENCE (2002)
Visualization of ATP release in pancreatic acini in response to cholinergic stimulus - Use of fluorescent probes and confocal microscopy
CE Sorensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
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IMMUNITY (2001)
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
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JOURNAL OF CELL BIOLOGY (2001)
Danger signals: SOS to the immune system
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CURRENT OPINION IN IMMUNOLOGY (2001)
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
NG Rainov
HUMAN GENE THERAPY (2000)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
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EMBO JOURNAL (2000)
Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
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